Job ID

REQ-10043483

Mar 07, 2025

Switzerland

Summary

Location: Basel, Switzerland

Full time, onsite, #LI-Onsite

We are seeking a highly motivated and curious lab-based Senior Scientist I whose focus will be on siRNA discovery in the xRNA Team within Biomedical Research in Basel. The team develops next-generation xRNA therapeutics in a collaborative and innovation driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will have a background in biology research with ideally a focus in RNA biology. The ideal candidate will have strong experience in medium - to high throughput screening using automation, cell culture techniques, assay development and technologies such as liquid handlers.

About the Role

Key Responsibilities:

• Design, plan and conduct routine siRNA screening in cell-based transfection assays using qPCR and reporter-based systems
• Perform novel assay development and optimization for cell-based assays with a focus on improving throughput with automation
• Contribute to designing, and developing automated workflows
• Operate automated liquid handling robotics platform
• Work collaboratively in a matrix-oriented environment and present work on a regular basis in unit meetings
• Acting as a point-of-contact in the team of day to day activities
• Document experiments in lab notebook, conduct data analysis, interpretation and present findings to team in a timely manner

Role Requirements:

• A higher degree in biology (such as Bachelor-s or Master-s), or Apprenticeship with equivalent industry experience in biochemistry, cell biology or related scientific discipline
• A minimum of 5 years of research experience gained ideally in a lab environment in a pharma and/or biotech industry setting
• Expertise in cell culture and conducting expression read outs (e.g. qPCR, Western Blot, ELISA)
• Experience with liquid handlers and automation of cell based assays
• Strong competence in MS office applications, expertise in Excel and maintenance of electronic Lab Notebooks
• Strong multi-tasking, organizational, attention to detail, verbal/written communication skills
• Ability to collaborate and thrive in fast-paced, team-oriented environment

Desired Requirements:

• Primary cell culture experience
• Expertise in Spotfire and/or GraphPad PRISM
• Expertise with BioMek or Opentrons liquid handlers

*Restrictions on flexible working may apply and are discretionary and can be discussed at interview, if applicable

• Accessibility and accommodation
  Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

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Division

Biomedical Research

Business Unit

Pharma Research

Location

Switzerland

Site

Basel (City)

Company / Legal Entity

C028 (FCRS = CH028) Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.