Novartis AG

Summary The Global Program Clinical Head (GPCH) is the global clinical leader responsible for one or more clinical programs across indications, involving one or multiple compounds. The GPCH owns the risk benefit assessment for the program(s), and as the leader of Global Clinical Team(s) (GCT) is accountable for the design, implementation, and execution of a clinical development program(s) to support decision milestones, regulatory requirements and market access. The GCPH may contribute to disease area strategy. About the Role The role reports into the Clinical Development Head. Your responsibilities will include: • Leads the GCT, represents Clinical Development on the Global Program Team (GPT) May serve as the Clinical Development Representative on NIBR clinical/project teams to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) May support Business Development & Licensing (BD&L) activities Post-Development Decision Point, leads the development and execution of the clinical strategy. Develops an endorsed Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or multiple treatment indications and/or multiple programs Leads the creation of clinical components of key documents (e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency with IDP and TPP. Supports registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Together with Patient Safety, ensures continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Serves as a core member of the Safety Management Team (SMT) As the medical expert, leads interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs (GMA), Marketing, Health Economics & Outcomes Research), and internal decision boards. Minimum Requirements: MD or equivalent (required) PhD (preferred) 5 years professional experience as MD and a minimum of 10 years of experience with clinical drug development in an industry environment spanning clinical activities in Phases I through III/IV and experience with leading submission dossiers (required) Ideally a Board certified Nephrologist OR extensive (> 5 years) experience in clinical development withing the Nephrology Therapeutic area Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data Thorough knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process required Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Operations Program Head (COPH) is accountable to deliver data-driven, actionable operational and strategic insights for execution of a clinical development program and all associated trials by representing GCO at the Global Clinical Team (GCT) as well as at the Global Program Team (GPT). The COPH is accountable to plan the strategic operationalization of clinical drug development programs and trials in line with the needs of the EPTs/GPTs. This specific COPH role may be focused within Cardiovascular programs. About the Role Major accountabilities: Lead operational delivery of the clinical development program and is responsible for the overall operational execution of the clinical program and related trials, as aligned with the IDP/CDP. Single GCO point of contact for assigned clinical development program and related trials. Key partner to GPCH during strategy, planning and execution stage of the program and related trials ensuring that the clinical science and strategy are consistently harmonized with an operationally feasible approach within the OEP-defined operational boundaries, so that the trials generate reliable information to answer the research questions and support decision making while protecting study participants. Leads operational delivery of the assigned program and related clinical trials and for all related strategic planning, prioritization of activities within that program and owns the early viability and feasibility assessment done by the GCO sub-teams as well as the development of operational scenarios for the execution of assigned programs and trials. Oversight and management of clinical trial budget for the assigned program and trials per OEP aligned with financial toll gates (e.g. IMB) and oversight of scope changes throughout the trial and program duration. Acts as a key partner to the GCO DU Head to use the operational insights developed with the GCO sub-team to actively shape the GDD DU strategy by driving the science of operations and GCO’s voice to ensure that the development strategy is operationally executable, thus contributing to both GCO and GDD DU mid to long term success. Is a key contact to senior leaders in GCO and beyond. Empowered to manage stakeholders, resolve conflict, and facilitate agreement. Actively monitor evolution and trends in Biopharmaceutical industry and may represent GCO and Novartis at Industry consortia. May be a member of Early Program Teams, providing an early and proactive assessment of operational viability of new clinical programs and ensuring that GCO’s assessment is correctly reflected in the overall program plans. In partnership with the GCO DU Head ensure that novel programs are reflected in the mid-long term GCO strategy and that GCO is prepared for their operationalization. The COPH champions a product oriented agile mindset, fostering a culture of experimentation combined with accountable delivery and overall high performance. Essential Requirements : Bachelors in life science/healthcare required; Advanced degree or equivalent education/degree in life sciences/ healthcare preferred (PhD/MD/ PharmD/ Masters) and 10+ years relevant experience in pharmaceutical drug development. Experience in managing associates globally and in management in a matrix organization. Proven ability to lead cross functional matrix teams applying product-oriented agile ways of working. Strong leadership, interpersonal and problem-solving skills. High resilience and ability to advocate and implement new ways of working. Extensive knowledge of clinical development processes, preferably extensive knowledge of Novartis late-stage development processes or high likelihood to develop it within 6 months after appointment. Proven ability to lead in times of organizational transformation and to lead across organizational boundaries. Strong knowledge of therapeutic area or high likelihood to develop it within 6 months after appointment. Strong matrix management skills for bridging stakeholders (business, scientific, technical) Strong relationship-building skills; can influence, negotiate with and motivate executive leadership This hybrid role can be based in London, Dublin or Basel. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Access Directors are dedicated to co-developing innovative and winning market access strategies, optimizing the payer value proposition and access-relevant evidence packages for assets, in partnership with the CLS and crossfunctional teams. They develop and implement transformative access solutions serving strategic disease areas (DAs) and maximizing IM assets, with focus on our priority geographic markets (CN, DE, JP), major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) needs and feasibility. Access Directors, • Represent access with internal partners and external stakeholders. Internally, drive vision, inspire and provide leadership throughout the Access community (International, Regions, Countries) and with key partners (CPS/International, Development, Biomedical Research, Operations, S&G, Regions and Countries). Externally, represent Novartis in appropriate fora and organizations to drive the Novartis strategic access agenda. • With International TA, develop and deliver all aspects of access strategy and execution for compounds/brands across the R-D-C continuum. • Collaborate and partner with TAs, Medical Affairs, Development and Biomedical Research to enhance the value proposition, access strategy and access-relevant evidence packages. Ensure access landscaping and payer evidence requirements are built into TPPs, clinical development plans, integrated product strategies, indication sequencing/asset maximization. • Enable asset strategy to translate science into payer and HCS value propositions and solutions, securing access, affordability, and contribute to wide scale patient access and efficiencies at scale. • With CLS and Pricing team, (co-)create the international pricing strategy and guidance. • With CLS, generate payer negotiation strategy, upskill and prepare countries for their payer negotiations. • With CLS, create innovative patient access and contracting approaches, Managed Entry Agreements (MEAs) and Patient Support Programs (PSPs) as required, to improve patient outcomes and support healthcare system affordability. • Ensure the appropriate and timely access inputs into IEPs, IPS, asset maximization incl. indication sequencing. • Create collaborative partnerships internally and externally to break down silos, partner across the value chain and shape the future of healthcare and markets. • Manage resource requirements to address asset/DA priorities. About the Role Key Responsibilities: Developing and operationalizing the Integrated Product Access strategy. Create and champion a compelling and competitive international strategic vision for how IM will innovate and expand access through DAs for the benefit of patients, Healthcare Systems, Payers, and Novartis Active leadership to enable broad country insights and alignment, and leverage external fora (e.g.,EMA/EUnetHTA & advisory boards) to pressure-test strategies, level of evidence etc. for feasibility and success With the TA, develop the international integrated product access strategy (IPAS) to deliver product differentiation most relevant to payers (e.g., well-defined target population, clinical endpoints, comparators, outcome measures, utility instruments, Health Economics data), patients, and HCS stakeholders worldwide. Ensure that at launch, Novartis brands are supported by a robust payer value proposition particularly featuring core elements; ‘Value for money’ story, strong value evidence package and a pricing strategy maximizing the lifetime value of the brand (including existing and future evidence to justify price) and the reputation of Novartis. Ensure access team develops and represents expert value evidence input into TPPs, clinical programs (including IEPs), BD&Ls, and develop any additional non-registration evidence to meet the needs of medical experts and institutions involved in reimbursement & access decisions for key geographies. Collaborate with the HEOR & PCO team to ensure full integration of adequate HEOR/evidence deliverables in high quality cross-franchise strategy. Ensure appropriate focus on priority markets needs into overall strategy. Ensure appropriate and timely access input into BD&Ls, asset maximization incl. indication sequencing. Maximize value of IM assets by creating and executing, together with TAs & pricing team, winning pricing strategies, global pricing guidance, incl. MEAs, PSPs, rigorous international pricing governance. Determine payer evidence requirements, risks/opportunities in the access landscape and create compelling access strategy with the TA and provide the “access toolbox” to share with priority markets (CN, DE, JP) major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) Stay abreast of internal and external developments, trends and other dynamics that affect the wider health policy and access domains, as well as of relevant scientific, clinical, and commercial developments. Analyse and anticipate changes in priority international markets (CN, DE, JP), major HTA archetypes (e.g.,UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) to model future expenditures and project critical market access assumptions. Collaborate with S&G and Development to drive consistent and access-optimal approaches to product shaping, value propositions and HCS value creation. Disseminate value of medicines to HCS decision-makers with focus on international forums and publications in collaboration with international or regional policy groups. Manage Access community and budgets. Effectively work in matrix balancing cross-functional perspectives and alignment with business priorities against flexible resourcing. Essential requirements: 5+ years of experience in market access roles 2+ years global or ex-US regional experience Experience working early in drug development lifecycle Product launch experience Cross functional and matrix influential experience across a team of multiple stakeholders Experience in driving commercial strategy driven through access or HEOR or pricing expertise Desirable requirements: MBA, Ph.D., M.D. or RPh. Strong external network with thought leaders and influencers in the payer and HTA environment 7+ years of experience in market access roles. 5+ years global or ex-US regional experience. Ex-US country experience. 2+ years of experience in the relevant therapeutic area Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a team of dedicated and smart people united by a drive to achieve together. You will drive portfolio policy for the Immunology and Neuroscience TAs and shape an industry-leading policy strategy to create an optimal policy environment for key Novartis portfolio assets. You will lead the early portfolio scanning process with Strategy & Growth for Immunology and Neuroscience and develop policy and advocacy strategies for key in-market and launch assets in these TAs in alignment with a broad range of cross-functional stakeholders. This role will shape the external environment to ensure fast and sustained access to innovation and position Novartis as a trusted partner with healthcare system stakeholders. About the Role Key Responsibilities: Represent Novartis externally in TA-specific fora and trade association working groups, with an expectation of leadership and agenda setting Develop and implement transformative policy solutions with focus on key brands and priority markets. Drive portfolio policy for the assigned TA and identify key policy priorities aligned with strategy and priorities for the NVS portfolio Lead early portfolio scanning process with Strategy & Growth for assigned TA and develop policy strategies and solutions for key in-market and launch assets in alignment with International TA Partner with cross-functional teams (e.g., V&A, patient advocacy, communications, medical, healthcare systems) to support design and implementation of policy strategy for assigned TA and to prepare favorable market conditions for priority pipeline assets Align with regions (Europe, APMA, LaCan) and direct reporting countries (US, CN, JP) on local policy priorities for TA. Articulate priority policy asks for advocacy activities in regions and key countries across the portfolio and align with regional PA Portfolio Advocacy leads to drive regional and local execution of advocacy activities in the TA Provide TA-specific thought leadership and insights for GPA-led engagements supporting healthcare system & policy change. Develop policy resources, coordinate global events and build coalitions within the TA and align and support implementation of deliverables with cross-functional advocacy partners. What you’ll bring to the role: ESSENTIAL CRITERIA Strong experience in life sciences policy and/or related fields, incl. policy focused patient advocacy. Experience with designing and executing market shaping strategies across multiple geographies External orientation, with strong external network and strong interpersonal and partnering skills Strategic sense and understanding of portfolio and commercial strategy development, ideally in assigned TA. Ability to develop senior management/Executive briefings on key policy issues and strategies Fluent In English DESIRABLE CRITERIA: Master’s degree in Regulatory Affairs, Pharmaceutical Sciences, Health Policy, or related field is preferred. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10046840 Apr 14, 2025 Switzerland Summary Location: JAPAT offices, Switzerland About the role: Would you like to be our Customer Service Support Specialist? At our company will be pivotal in providing high-quality service and hospitality to our notable clientele. This role requires the individual to uphold the company-s high service standards and to anticipate unique client needs. The ideal candidate will play an integral role in enhancing our client-s customer experience. If you're driven by a passion for customer service and aspire to make a meaningful impact, we invite you to join us. This role will require an individual comfortable with flexible work hours as part of a 50% work schedule and should ideally live within a 30-minute radius of Basel airport to accommodate early morning and/or late evening and weekend assignments when necessary. About the Role Key Responsibilities: Provide exceptional customer service to our VIP customers, corporate management, and board members, Utilize strong problem-solving skills to work calmly and efficiently under pressure, responding readily to any ad-hoc requirements or queries. Demonstrate high emotional intelligence and empathy to anticipate and meet the needs of distinguished clients. Showcase detail orientation and maintain the highest standards in service and presentation, providing a clean and pristine environment. Display organizational skills to smoothly coordinate all procedures and schedules while managing time effectively. Engage productively with all departments, assisting with general support activities and ensuring seamless cross-departmental collaboration. Show discretion and trustworthiness, exhibiting a positive and friendly demeanor. Essential Requirements: Several years' experience in high-level customer service, ideally in aviation, luxury hospitality/concierge services, executive assistant roles or as a Corporate Flight Attendant. Excellent communication skills in German and English; knowledge of French would be advantageous. Familiarity with Novartis is a plus Experience with VIP clients and high-ranking business individuals. Able to display excellent host qualities and a warm, inviting demeanor to team members and passengers alike. Displays exceptional detail-orientation and a commitment to maintaining the highest standards in service and presentation. Comfortable with flexible work hours as part of a 50% work schedule and should ideally live within a 30-minute radius of Basel airport to accommodate early morning and/or late evening and weekend assignments when necessary. Languages: Fluent in English and German, French preferred. Benefits and rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Corporate Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C071 (FCRS = CH071) Japat AG Functional Area Facilities & Administration Job Type Part time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We’re a team of dedicated and smart people united by a drive to achieve together. You will drive portfolio policy for Oncology and shape an industry-leading policy strategy to create an optimal policy environment for key Novartis portfolio assets. You will lead the early portfolio scanning process with Strategy & Growth for assets and develop policy and advocacy strategies for key in-market and launch assets in alignment with a broad range of cross-functional stakeholders. Oncology will be in particular focus beyond innovative platforms. Showing deep knowledge of the pharmaceutical business model, healthcare systems, and political and economic environment, this role will proactively shape the external environment to ensure fast and sustained access to innovation and position Novartis as a trusted partner with healthcare system stakeholders. About the Role Key Responsibilities: Represent Novartis externally in TA-specific fora and trade association working groups, with an expectation of leadership and agenda setting. Develop and implement transformative policy solutions with focus on key brands and priority markets. Drive portfolio policy for the assigned TA and identifykey policy priorities alignedwith strategy and priorities for the NVS portfolio Lead early portfolioscanningprocesswith Strategy & Growth for assigned TA and develop policy strategies andsolutionsfor key in-market and launch assets in alignment with International TA. Partner with cross-functional Teams (e.g.V&A,patientadvocacy,communications, medical,healthcaresystems) to supportdesignandimplementation ofpolicystrategy for assigned TA and to prepare favorable market conditions for priority pipeline assets. Align with regions (Europe, APMA, LaCan) anddirectreporting countries (US,CN,JP)on local policyprioritiesfor TA. Articulate priority policy asks for advocacy activities inregionsand keycountriesacross the portfolio and align with regional PA Portfolio Advocacy leadsto driveregionaland localexecution ofadvocacyactivities in the TA. Provide TA-specific thought leadership and insights for GPA-led engagements supportinghealthcare system & policy change. Develop policy resources, coordinateglobal events and build coalitions within the TA and align and support implementation of deliverables with cross-functional advocacy partners. Based on a strong external network, build policy partnerships and coalitions as required. Provide policy thought leadership for Global Public Affairs led engagements that support healthcare system and policy change conducive to the Novartis portfolio. What you’ll bring to the role: ESSENTIAL CRITERIA: Extensive experience in therapeutic area-related related life sciences policy and/or related fields, incl. policy focused patient advocacy. Established, public leadership position in Oncology related trade association working group and/or public fora, media. Experience representing the pharmaceutical industry in policy environment, with track record of measurable business impact with business and organizational awareness, enterprise perspective. Experience with designing and executing market shaping strategies across multiple geographies. Strategic sense and understanding of portfolio and commercial strategy development. Fluency in English. DESIRABLE CRITERIA: Master’s degree in relevant discipline / Advanced degree (PhD, MBA, or equivalent) in Pharmaceutical Sciences, Health Economics, Public Policy, or a related field. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10027583 Apr 17, 2025 Switzerland Summary We-re a team of dedicated and smart people united by a drive to achieve together. You will drive portfolio policy for Oncology and shape an industry-leading policy strategy to create an optimal policy environment for key Novartis portfolio assets. You will lead the early portfolio scanning process with Strategy & Growth for assets and develop policy and advocacy strategies for key in-market and launch assets in alignment with a broad range of cross-functional stakeholders. Oncology will be in particular focus beyond innovative platforms. Showing deep knowledge of the pharmaceutical business model, healthcare systems, and political and economic environment, this role will proactively shape the external environment to ensure fast and sustained access to innovation and position Novartis as a trusted partner with healthcare system stakeholders. About the Role Key Responsibilities: Represent Novartis externally in TA-specific fora and trade association working groups, with an expectation of leadership and agenda setting. Develop and implement transformative policy solutions with focus on key brands and priority markets. Drive portfolio policy for the assigned TA and identify-key policy priorities aligned-with strategy and priorities for the NVS portfolio- Lead early portfolio-scanning-process-with Strategy & Growth for assigned TA and develop policy strategies and-solutions-for key in-market and launch assets in alignment with International TA. Partner with cross-functional Teams- (e.g.-V&A,-patient-advocacy,-communications, medical,-healthcare-systems) to support-design-and-implementation of-policy-strategy for assigned TA and to prepare favorable market conditions for priority pipeline assets. Align with regions (Europe, APMA, LaCan) and-direct-reporting countries (US,-CN,-JP)-on local policy-priorities-for TA. Articulate priority policy asks for advocacy activities in-regions-and key-countries-across the portfolio and align with regional PA Portfolio Advocacy leads-to drive-regional-and local-execution of-advocacy-activities in the TA. Provide TA-specific thought leadership and insights for GPA-led engagements supporting-healthcare system & policy change. Develop policy resources, coordinate-global events and build coalitions within the TA and align and support implementation of deliverables with cross-functional advocacy partners. Based on a strong external network, build policy partnerships and coalitions as required. Provide policy thought leadership for Global Public Affairs led engagements that support healthcare system and policy change conducive to the Novartis portfolio. What you-ll bring to the role: ESSENTIAL CRITERIA: Extensive experience in therapeutic area-related related life sciences policy and/or related fields, incl. policy focused patient advocacy. Established, public leadership position in Oncology related trade association working group and/or public fora, media. Experience representing the pharmaceutical industry in policy environment, with track record of measurable business impact with business and organizational awareness, enterprise perspective. Experience with designing and executing market shaping strategies across multiple geographies. Strategic sense and understanding of portfolio and commercial strategy development. Fluency in English. DESIRABLE CRITERIA: Master-s degree in relevant discipline / Advanced degree (PhD, MBA, or equivalent) in Pharmaceutical Sciences, Health Economics, Public Policy, or a related field. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Corporate Affairs Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area Communications & Public Affairs Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Ulcerative colitis and Crohn's disease, along with other gastrointestinal ailments, represent a diverse array of conditions impacting millions globally. These afflictions have significant unmet medical needs and often lead to a diminished quality of life. Novartis stands at the forefront of pharmaceutical innovation in immunology, leveraging advanced scientific research to develop transformative treatments that enhance patients' lives worldwide. We are seeking a Medical Director or Executive Director of Gastrointestinal (GI) Immunology in Translational Medicine Immunology. Join us in this endeavor! You will provide medical and scientific leadership and expertise in a role that significantly impacts the drug development pipeline. 1. Drive success of early global programs, develop and implement strategies to achieve Transition Decision Point (TDP) 2. Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. 3. Support Translational Research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. 4. Provide scientific expert assessments and support for in-licensing opportunities, including due diligences. About the Role Major Accountabilities Early clinical projects (Phase I / II, “Discovery”): Develop, in collaboration with TM TA Head and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications, including post-indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Convene relevant (internal and external) experts to consider the proposed approach to reach TDP; present plans for approval at relevant decision boards. Be responsible for clinical portions of the Integrated Development Plan (IDP, including the Clinical Development Plan and Clinical Profiling Plan) Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Late-stage clinical projects (post-TDP, “Profiling”): In collaboration with TM TA Head or Translational Medicine Profiling Head: Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials, such as special populations, drug-drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc. Drive analysis of studies and presents results to relevant decision boards. Communicate clinical team matters to GPTs and relevant BR and Development boards [and other Novartis Boards] Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Be responsible for writing TM portion of documents needed for regulatory submission through drug registration (including advisory committee and scientific advice group meetings) Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with TM TA Head, BR Research scientists, other TM line functions (BMD, CS&I, PCS, PKS), develop strategies to identify initial or expansion (PIE) indications, and to obtain sufficient evidence to fund these ideas. In collaboration with research scientists, identify, develop, and implement strategy for preclinical support of clinical program-related scientific objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities. This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Be accountable for compound-related biomarker strategies; works closely with Biomarker Expert in implementation. Business Development and Licensing (BD&L; in-licensing and outlicensing compounds): Participate on BD&L teams as the TM representative. In collaboration with BD&L team, evaluate the risks and benefits of potential in-licensing opportunities, identifying the strengths and weaknesses of external programs in terms of TM’s scope of responsibility. Participate in teams carrying out out-licensing of BR programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. Leadership: Lead study-specific teams/ clinical trial teams in partnership with other line functions. Lead BR-sub-team(s) on Global Project Teams for late-phase programs Collaborate closely with other TM (especially CS&I) and non-TM (especially Project Man- agement) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific stand- ards and innovation. Key Performance Indicators Delivery of proposed Development Candidate ((B)DC) and Integrated Development Plan Approval (IDPA) milestones, and results driving decision-making for/against transition into later phase development (TDP), according to defined timelines. Delivery of Clinical pharmacology and profiling strategy including execution of studies according to timelines to support regulatory submissions and approvals. Delivery of TR plans, whether in vitro, in vivo, or in silico, to drive program strategy and clinical trial efficiency. Team leadership skills that create high performing teams and drive efficient conduct of innovative, interpretable clinical results and a focus on operational excellence at all levels. Strong adherence to and modeling of Novartis values and behaviors. Impact of this role? Design and implementation of early Integrated Develop- ment Plan (IDP) and design and implementation of studies according to the IDP, enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds. This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via the TDP mechanism, and driving the program after TDP by delivering key Profiling data to support regulatory submissions. Recognized Expert in field, drives project team clinical strategy. Works globally across Novartis. Role Requirements : Education Doctoral degree, MD required in most cases. PhD or relevant scientific experience with academic track record preferred Demonstrated excellence and clinical expertise in relevant medical subspecialty. Experience/Professional Requirement: At least 5 years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with level of role. Innovation: Seeks out new clinical discovery opportunities and approaches to reach TDP. Demonstrated passion for science. Recognized expert in field, driving success for individual studies and projects; respected by colleagues across R&D, Development, and externally. Languages: Fluent English (oral and written). ABOUT TRANSLATIONAL MEDICINE: Translational Medicine is a global group of scientists and Physicians working at the pre-clinical and early clinical stage of drug discovery. Our Physician-Scientist Discovery & Profiling group drives innovative and cutting–edge science from Discovery to the market through the selection, profiling and effective global development of successful medicines. The group closes the gap between preclinical research and clinical development and integrates clinical science into the discovery and preclinical development phase. Our Translational Medicine concepts are driven by medical needs of the patient and the concept of personalized medicine, tailoring the drug, its dose and dosing regimen in such way to the patient that the clinical response is optimal in terms of efficacy and safety. We focus from identification of drug targets (molecular pathways relevant to disease) up to the completion of Proof of Concept (Phase IIa studies). Our Translational Medicine Experts are part of preclinical project teams in all drug discovery phases and help design the pathway for First in Human studies (healthy volunteer) that bridge to studies in the patient population. They have the comprehensive responsibility for designing and executing the early clinical drug development phase together with a project team from researcher, biomarkers, biostatistics, modeling and simulation, toxicology, technical experts and the clinical trial teams. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Play a key role in our QC team in BDSS, Klybeck by testing drug substances the results of which not only support our global Novartis Biotech network but also our R&D activities. As a QC Analyst II you will use bioanalytical laboratory skills to test and measure products or materials while ensuring that analysis is performed according to established Standard Operating Procedures (SOPs) & analytical methods. About the Role Analytical testing /documentation of drug product / finished product / complaints / stability / packaging material samples to GxP standards Stability -Testing Sample storage and management . Analytical documentation of stability samples to GxP standards Orders are processed correctly and quickly. No waiting times due to wrong or delayed order. Deadline adherence rate: orders completed on time, all missed deadlines reported in good time, the shortest possible lead time Ensure constant readiness for inspection, no critical complaints from superiors and inspectors Consistently follow the GMP and GSU guidelines, as well as the SOPs, no critical irregularities Requirements: Sound technical & scientific knowledge of pharmaceutical/ bioanalytics Working experience in Laboratory environment in pharma Analytics/QC/ELISA equivalent. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10039768 Apr 17, 2025 Switzerland Summary Play a key role in our QC team in BDSS, Klybeck by testing drug substances the results of which not only support our global Novartis Biotech network but also our R&D activities. As a QC Analyst II you will use bioanalytical laboratory skills to test and measure products or materials while ensuring that analysis is performed according to established Standard Operating Procedures (SOPs) & analytical methods. About the Role Analytical testing /documentation of drug product / finished product / complaints / stability / packaging material samples to GxP standards Stability -Testing Sample storage and management . Analytical documentation of stability samples to GxP standards Orders are processed correctly and quickly. No waiting times due to wrong or delayed order. Deadline adherence rate: orders completed on time, all missed deadlines reported in good time, the shortest possible lead time Ensure constant readiness for inspection, no critical complaints from superiors and inspectors Consistently follow the GMP and GSU guidelines, as well as the SOPs, no critical irregularities Requirements: Sound technical & scientific knowledge of pharmaceutical/ bioanalytics Working experience in Laboratory environment in pharma Analytics/QC/ELISA equivalent. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Quality Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated and curious Research Scientist whose focus will be on small-scale siRNA synthesis in our xRNA synthesis team at Biomedical Research in Basel. Our team produces next-generation xRNA therapeutics in a collaborative- and innovation-driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will be responsible for producing and purifying high-quality oligonucleotides, and also to contribute to our innovation efforts in siRNA chemistry. Join us and help reimagine medicine! About the Role Your responsibilities Plan and execute small scale oligonucleotide synthesis on automated synthesizers Conduct deprotection, purification, annealing, and routine analytical characterization, in autonomy Analyse and communicate scientific results at internal meetings Collaborate with a highly dynamic team of RNA scientists Maintain a high standard in laboratory safety and working practices What you will bring to the role A Bachelor or Master degree, with a focus on synthetic organic chemistry (please note that we do not require a PhD level candidiate for the position at this time) Prior experience with small-scale oligonucleotide synthesis and DNA synthesizers (e.g. K&A, MerMade) is considered a plus Passion for oligonucleotide chemistry and experimentation in a wet lab Possessing a critical thinker's perspective, capable of formulating innovative hypotheses Interest in ground-breaking technological and scientific trends such as novel drug modalities and automation, especially regarding their potential use in drug discovery and development. A collaborative mindset, with an enthusiasm to develop yourself and others A commitment to delivering high-quality data Aptitude to work in a fast-paced, team-oriented matrix environment Excellent oral and written communication skills *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10046778 Apr 03, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated and curious Research Scientist whose focus will be on small-scale siRNA synthesis in our xRNA synthesis team at Biomedical Research in Basel. Our team produces next-generation xRNA therapeutics in a collaborative- and innovation-driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will be responsible for producing and purifying high-quality oligonucleotides, and also to contribute to our innovation efforts in siRNA chemistry. Join us and help reimagine medicine! About the Role Your responsibilities Plan and execute small scale oligonucleotide synthesis on automated synthesizers Conduct deprotection, purification, annealing, and routine analytical characterization, in autonomy Analyse and communicate scientific results at internal meetings Collaborate with a highly dynamic team of RNA scientists Maintain a high standard in laboratory safety and working practices What you will bring to the role A Bachelor or Master degree, with a focus on synthetic organic chemistry (please note that we do not require a PhD level candidiate for the position at this time) Prior experience withsmall-scale oligonucleotide synthesisand DNA synthesizers (e.g. K&A, MerMade) is considered a plus Passion foroligonucleotide chemistry and experimentation in a wet lab Possessing a critical thinker's perspective, capable of formulating innovative hypotheses Interest in ground-breaking technological and scientific trends such as novel drug modalities and automation, especially regarding their potential use in drug discovery and development. A collaborative mindset, with an enthusiasm to develop yourself and others Acommitment to delivering high-quality data Aptitude to work in a fast-paced, team-oriented matrix environment Excellent oral and written communication skills *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary ~Entwicklung und Wartung von Automatisierungshardware, -software und -prozessen, die diese Geräte verwenden, um komplexe Experimente durchzuführen, die mit herkömmlichen Labortechniken nicht durchgeführt werden können. Führt Programmierung und Analyse für Robotik durch. Bietet Unterstützung für High-Through-Put Compound Screening und andere Assay-Techniken, wie entwickelt und benötigt. Unterstützt, entwickelt und initiiert die Automatisierung wissenschaftlicher Prozesse und Programme. Kann System und Prozesse validieren. About the Role Your responsibilities: Provide technical support on laboratory automation systems in close alignment with the local operators. Analyze processes, software and hardware issues and identify root causes of malfunctions, seek advice from vendors or experienced co-workers when required and conduct repairs in alignment with team or vendors where applicable Set up and manage vendor onsite interventions and preventative maintenances Pursue open issues with vendors until resolved in timely manner Establish, monitor and maintain a stable and productive automation environment through QC, preventative maintenance and excellent documentation Plan, manage and execute automation projects from new devices, over upgrades to existing systems up to complex installations, in alignment with the local and the globally distributed team. Assist business with requirements engineering across functional units (Compound Management, IT) Assist business owners with business analysis and documentation in the specifying and planning of complex workflows and their automated execution. Assist business owners in the selection of adequate automation hardware (liquid handling and peripheral devices) Actively seek input and feedback from the Compound Management team members to identify gaps in processes or with existing automation platforms to elaborate and propose improvements Communicate transparently on all aspects of the daily work Requirements: Degree qualified or equivalent in a relevant discipline with + 5 years’ experience in automation, ideally lab automation. Deep understanding of liquid handling principles and technologies, has multi-year experience with different vendors of liquid handling equipment (e.g., Hamilton, Tecan, CyBio, others) Has worked in or has lead projects for laboratory automation or equivalent ·Experience with business analysis and can develop automation solutions IT friendly - profound understanding of software driving automated systems and liquid handling systems (Venus, Evo Ware, Momentum, Cellario, Green Button Go, etc.), databases, script and protocol programming You are not afraid to work with scripting or programming languages Open communication, self-motivated and self-organized, excellent team working skills and a flexible working perception are important ·Languages: English, German, (French is a plus) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10045608 Apr 15, 2025 Switzerland Summary ~Entwicklung und Wartung von Automatisierungshardware, -software und -prozessen, die diese Geräte verwenden, um komplexe Experimente durchzuführen, die mit herkömmlichen Labortechniken nicht durchgeführt werden können. Führt Programmierung und Analyse für Robotik durch. Bietet Unterstützung für High-Through-Put Compound Screening und andere Assay-Techniken, wie entwickelt und benötigt. Unterstützt, entwickelt und initiiert die Automatisierung wissenschaftlicher Prozesse und Programme. Kann System und Prozesse validieren. About the Role Your responsibilities: Provide technical support on laboratory automation systems in close alignment with the local operators. Analyze processes, software and hardware issues and identify root causes of malfunctions, seek advice from vendors or experienced co-workers when required and conduct repairs in alignment with team or vendors where applicable Set up and manage vendor onsite interventions and preventative maintenances Pursue open issues with vendors until resolved in timely manner Establish, monitor and maintain a stable and productive automation environment through QC, preventative maintenance and excellent documentation Plan, manage and execute automation projects from new devices, over upgrades to existing systems up to complex installations, in alignment with the local and the globally distributed team. Assist business with requirements engineering across functional units (Compound Management, IT) Assist business owners with business analysis and documentation in the specifying and planning of complex workflows and their automated execution. Assist business owners in the selection of adequate automation hardware (liquid handling and peripheral devices) Actively seek input and feedback from the Compound Management team members to identify gaps in processes or with existing automation platforms to elaborate and propose improvements Communicate transparently on all aspects of the daily work Requirements: Degree qualified or equivalent in a relevant discipline with + 5 years- experience in automation, ideally lab automation. Deep understanding of liquid handling principles and technologies, has multi-year experience with different vendors of liquid handling equipment (e.g., Hamilton, Tecan, CyBio, others) Has worked in or has lead projects for laboratory automation or equivalent ·Experience with business analysis and can develop automation solutions IT friendly - profound understanding of software driving automated systems and liquid handling systems (Venus, Evo Ware, Momentum, Cellario, Green Button Go, etc.), databases, script and protocol programming You are not afraid to work with scripting or programming languages Open communication, self-motivated and self-organized, excellent team working skills and a flexible working perception are important ·Languages: English, German, (French is a plus) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No

Summary Location: Basel, Switzerland Role Purpose: We are looking for a process chemist / chemical engineer to support the department Chemical & Analytical Development as part of the Global Technical R&D department of Global Drug Development. In this role you will have operational end-to-end responsibility within the Local Supply Center (LSC) for clinical supplies in early and late phase development of the assigned projects in different modalities (e.g. synthetic oligonucleotides, peptide synthesis, small molecules, bioconjugate manufacturing). You represent the LSC in chemical and pharmaceutical project sub teams and directly influence process development by providing expertise in scaling up the processes. About the Role Major Accountabilities Process Development and Improvement: Actively contributes to process development by providing expertise in scaling up chemical processes. Participates in assigned non-project-related activities within the LSC, such as leading and executing business process improvement initiatives and collaborating in cross-functional working parties. Collaborates on capital investment projects. Project Representation and Coordination: Represents the LSC in chemical and pharmaceutical project subteams and serves as the main contact between development units for assigned projects. Frequently works on several projects simultaneously. Prepares synchronization of synthesis and cost estimation for assigned campaigns. Evaluates suppliers in collaboration with the project team and places purchase orders for raw materials as appropriate. Operational Responsibilities: Holds operational end-to-end responsibility for the supply of assigned projects within LSC. Determines the suitability and availability of appropriate process equipment and suggests modifications as needed. Monitors the progress of process development in mitigating identified processing and safety risks. Troubleshoots processes as appropriate and assesses the potential impact of any process deviation and intended changes for future batches. Safety and Compliance: Early identification of processing hurdles and safety concerns and suggests alternatives. Attends and evaluates safety assessments of lab and plant processes for assigned steps. Documentation and Training: Writes Plant Master Procedures (PMP). Establishes appropriate campaign documentation (e.g., campaign experience report, cost estimation, production scenarios, registration documentation). Trains the manufacturing team on processes based on PMP and provides guidance during batch execution. Implements and trains operational staff on new regulations, policies, and SOPs authored. Work Experience Desired: 3 to 4 years of practical experience in chemical / pharmaceutical industry or > 4 years of experience in field of expertise. Also seen as potential entry position for talents with strong leadership attributes. Good (IT) application know how. Good knowledge about the Drug Development process. Comprehensive knowledge about project management. Knowledge of relevant regulations (e.g. GMP, HSE etc.) and specific standards. Demonstrates cross-functional problem-solving and idea generation skills. Advanced presentation skills. Excellent organization and planning skills Experienced in programming / data mining Ability to work in interdisciplinary and cross-cultural teams. Language German English Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Join our dynamic team at Novartis! You'll lead and oversee Global Equity Projects, ensuring top-notch Governance and Compliance for our equity plans and policies. Be at the forefront of supporting and monitoring the development and implementation of our Long Term Incentive Equity plans. Your role will be pivotal in shaping policies, practices, and procedures that drive our success. About the Role Your responsibilities include, but not limited to: Tax Compliance / Employment Tax Oversee daily equity tax compliance activities Coordinate and monitor global equity tax and payroll compliance with external vendors and other functions Review global tax fact-sheets with external vendors and guide communication to plan participants and payroll teams Co-manage automation of payroll instructions and variance reporting, leading post-implementation processes Ensure equity employment tax compliance, liaising with employment tax and payroll tax teams to provide clear instructions to global payroll teams Equity Administration / Management Oversee equity program data maintenance Develop and maintain communication material for participants and internal clients Seek for opportunities & coordinates system developments within Equity Function Provide advice and liaise with the P&O functions on equity related matters Lead global cross-functional equity projects Support the equity grant and vesting processes as well as daily activities Finance / Treasury Compliance Lead operational reporting (monthly, quarterly, annual reporting as required) to Global and local FRA Monitor daily equity administration and links with FRA and treasury departments Coordinate Financial aspects and be the first point of contact for Global BPA / FRA for Cash and Equity Plans Coordinate activities with and inputs to external auditors Monitors compliance and governance in equity transactions What you’ll bring to the role: Relevant degree (e.g. Business, Economics or Finance), Advanced degree preferred Proficiency in English required – spoken & written, other languages is an asset. Significant experience gained in Equity management within a corporate global environment Relevant experience with Employment tax & compliance in equity matters Demonstrated Financial reporting experience in equity matters Experience leading Global Projects in equity, tax or global Strong understanding of rewards practices Ability to deal with highly complex environment, reducing complexity into strategy decision recommendations Strong communication skills, and experience working across geographies and cultures. Excellent analytical skills linked with conceptual thinking capabilities Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated and curious Senior Scientist whose focus will be on siRNA Analytics and Automation in our xRNA synthesis team at Biomedical Research in Basel. Our team produces next-generation xRNA therapeutics in a collaborative- and innovation-driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will have strong experience in analytical chemistry, will be responsible for delivering high-quality analytical data, and for incorporating innovative methodologies for our xRNA platform. Join us and help reimagine medicine! About the Role Your responsibilities Run Mass Spectrometry analytics of oligonucleotide samples by state-of-the-art methods and technologies Develop and introduce innovative separation methods for HPLC or FPLC based-systems Monitor the field for new developments and techniques in oligonucleotide analytics Contribute to our high-throughput, automated synthesis efforts Together with the project team, integrate experimental data to develop scientific hypotheses and prioritize novel oligonucleotide chemistries to address key project questions Support and coach other team members by sharing your know-how and experience Discuss and communicate scientific results at internal meetings and research boards Responsibility to maintain high levels of laboratory safety and infrastructure What you will bring to the role A Bachelors or Master degree with a focus on analytical or synthetic chemistry Experience with oligonucleotide analytics or downstream processing is considered a plus Exposure to and knowledge of Mass Spectrometry Experience with liquid handling robotic systems (e.g. Hamilton, Tecan) is considered a plus Experience with scripting languages (e.g. R, Python) is considered a plus Passion for analytical technologies and lab automation Ability to critically interpret results, develop and implement novel methodologies and processes by taking calculated risks and smart decisions A collaborative mindset, with an enthusiasm to develop yourself and others A commitment to delivering high-quality data Aptitude to work in a fast-paced, team-oriented matrix environment Excellent oral and written communication skills *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Data42 is an innovative data and analytics program that leverages the power of data science and artificial intelligence to transform medical research and development. At Novartis we are reimagining Medicine via scientific innovation and data-driven decision making. Data42 allows us to integrate multimodal data in a securely governed platform. The Data42 team is part of Novartis Biomedical Research, where we discover and develop innovative treatments across several therapeutic areas like Oncology, Immunology, Cardiovascular and Neuroscience. We are looking for a director-level Real World Data Scientist to join our Data42 team. Your role is to work on innovative solutions to support Novartis’s Medical Affairs organization and to leverage our internal and RWD to improve patient care and outcomes. In your role you will connect the Data42 team with our Medical Affairs Organization to deliver high impact with the use of data. We are seeking a scientific leader who wants to combine their medical and regulatory knowledge with cutting edge data science to improve patients’ lives. If collaboration energizes you – this role is for you. Apply today and we can innovate together! This role will be based in Basel, Switzerland, Dublin, Ireland in a hybrid working approach. About the Role This role is all about understanding RWD and clinical data, serving science and innovation, connecting the right skills together to contribute to medical evidence generation. Being part of Biomedical Research, the vision is to empower and inspire Novartis’ Research and Development organizations by harnessing inter-connected multimodal and external data in our securely governed platform. You will be a key contributor to the medical affairs data and technology strategy, thus enabling priority enterprise projects. As a leader within data42, you will contribute to the continuous evolution of the data42 team with enthusiasm, cooperation and a collaborative attitude. Major accountabilities but not limited to: Co-create and execute of innovative data analytics solutions with key stakeholders across Medical Affairs. Collaborate with cross-functional teams to identify data and co-create analytic applications to support high quality analyses of clinical and real-world data. Provide expertise on internal and external regulations, guidelines, and best practices to ensure compliance. Stay abreast of emergent applications, trends and insights, and positively drive development of advanced analytic capabilities to ensure data42 continuously evolves as a well-recognized platform that addressed the ever-changing data and analytic environment Develop strong internal and external partnerships to promote effective collaborations. Lead by example in promoting a collaborative and entrepreneurial culture and mindset. Be an agent for change and engage support for innovative ideas, methods, technologies, partnerships, and solutions. Support project ideation with Medical Affairs stakeholders to execute a data and technology strategy through integrating access to multimodal data (e.g. real-world data, clinical data, genomics, biomarkers, imaging) to support real world evidence generation, and applying innovative methods, models (e.g. in-silico trials), and technology Excellent communicator and advocate for data-driven decision-making to align with Novartis' overall strategy and improve patient care outcomes. Ensure data42’s enablement of priority initiatives for RWE, such as pooling data42 data sources to address innovative evidence needs in a specific disease indication. Represent Data42 externally at conferences Your Experience: PhD or MD in a quantitative discipline like statistics or epidemiology with experience across disease areas 10+ years in quantitative science leadership roles, with deep understanding of the entire product value chain within the pharmaceutical industry. Proven track record in providing impact with RWD applying advanced analytics as well as ML/AI. Extensive experience and knowledge in evidence generation, including analyzing clinical and real-world data, and understanding evidence generation study methodologies. Strong leadership experience (10+ years), engaging stakeholders at any level of the organization. Operational experience with the end-to-end R&D process and successful guidance of drug programs through clinical development. 5+ years’ experience in building partnerships and engaging stakeholders at senior levels across the entire product value chain Familiar with SQL, Python, R, Jupyter Notebooks etc Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10031499 Mar 11, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: Defines, leads and manages the analytical project strategy including the overall analytical control strategy for Drug Substance(s) and Drug Product(s) in line with the overall CMC project development plan; ensures project specific high quality analytical submission documents and ready for inspection status at all time; support/coach analytical team members and thereby contribute to the overall Technical Research & Development strategy and objectives. About the Role As part of the Analytical Research and Development group, this is a new role waiting for you to put your own stamp on it. The position is located at the Novartis Headquarter site in Basel within the Technical R&D (TRD) department of Global Drug Development. Your responsibilities Your responsibilities include but are not limited to : Formulating, developing and driving an overall science, quality and regulatory driven analytical project strategy including contingency plans and risk evaluations in the course of clinical development (API and formulated drug product, essentially small molecules intended for oral administration). Leading and overseeing analytical activities throughout drug development within a global project team such as specification setting, method development and validation, stability and release testing. Activities may cover pre-clinical support, early/late phase clinical development as well as transfer to commercial operations and registration. Being a core member of the technical development sub-team, representing Analytical Research & Development; co-owning the technical development in partnership with Chemical and Pharmaceutical Development; contributing actively to the elaboration of the overall CMC technical development plan and driving state of the art control strategy. Accountability to meet quality, timelines and budget for assigned projects, defining clear analytical project plans Managing interactions with internal and external stakeholders, including potential outsourced activities Proactively identifying potential scientific, technological and GMP gaps, proposing creative solutions and ensuring appropriate communication within and across units Providing input into CMC documents to support regulatory submissions Acting as the analytical project representative in peer reviews as well as internal and external audits Supporting the analytical project teams with quality awareness, strategic input, scientific and technical expertise in a phase dependent manner Strong contribution to advance science, technology and innovation within Analytical R&D What you-ll bring to the role: Minimum BS / MS in analytical chemistry with relevant experience in industry, PhD in analytical chemistry or equivalent desirable Minimum 3-5 years- experience in the pharmaceutical industry, preferably in analytical development and/or quality control Experience in managing projects ideally in a global matrix environment Strong quality focus, experience in a GMP environment Understanding of regulatory expectations and profound scientific knowledge in analytical development (e.g. Chromatography, dissolution rate, titration, physical state etc...) Fluent in English (oral and in writing) Ability to perform in a highly dynamic environment You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process – both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams’ culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Defines, leads and manages the analytical project strategy including the overall analytical control strategy for Drug Substance(s) and Drug Product(s) in line with the overall CMC project development plan; ensures project specific high quality analytical submission documents and ready for inspection status at all time; support/coach analytical team members and thereby contribute to the overall Technical Research & Development strategy and objectives. About the Role As part of the Analytical Research and Development group, this is a new role waiting for you to put your own stamp on it. The position is located at the Novartis Headquarter site in Basel within the Technical R&D (TRD) department of Global Drug Development. Your responsibilities Your responsibilities include but are not limited to : Formulating, developing and driving an overall science, quality and regulatory driven analytical project strategy including contingency plans and risk evaluations in the course of clinical development (API and formulated drug product, essentially small molecules intended for oral administration). Leading and overseeing analytical activities throughout drug development within a global project team such as specification setting, method development and validation, stability and release testing. Activities may cover pre-clinical support, early/late phase clinical development as well as transfer to commercial operations and registration. Being a core member of the technical development sub-team, representing Analytical Research & Development; co-owning the technical development in partnership with Chemical and Pharmaceutical Development; contributing actively to the elaboration of the overall CMC technical development plan and driving state of the art control strategy. Accountability to meet quality, timelines and budget for assigned projects, defining clear analytical project plans Managing interactions with internal and external stakeholders, including potential outsourced activities Proactively identifying potential scientific, technological and GMP gaps, proposing creative solutions and ensuring appropriate communication within and across units Providing input into CMC documents to support regulatory submissions Acting as the analytical project representative in peer reviews as well as internal and external audits Supporting the analytical project teams with quality awareness, strategic input, scientific and technical expertise in a phase dependent manner Strong contribution to advance science, technology and innovation within Analytical R&D What you’ll bring to the role: Minimum BS / MS in analytical chemistry with relevant experience in industry, PhD in analytical chemistry or equivalent desirable Minimum 3-5 years’ experience in the pharmaceutical industry, preferably in analytical development and/or quality control Experience in managing projects ideally in a global matrix environment Strong quality focus, experience in a GMP environment Understanding of regulatory expectations and profound scientific knowledge in analytical development (e.g. Chromatography, dissolution rate, titration, physical state etc...) Fluent in English (oral and in writing) Ability to perform in a highly dynamic environment You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10045494 Apr 08, 2025 Switzerland Summary As a Clinical Development Medical Director, you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. The Clinical Development Medical Director (CDMD) is the clinical leader of defined program level activities (e.g., submission activities, briefing books, clinical study reports, etc.) and/or a large, complex trial, under the leadership of the Global Program Clinical Head (GPCH). May also lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase). About the Role Major accountabilities: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the clinical development plan (CDP), data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., investigator brochures, briefing books, safety updates, submission dossiers, and responses to health authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors, and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert (CSE). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team, and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Clinical Development Head by providing medical input into CDP and clinical trial package reviews and contributing/driving development of disease clinical standards for disease areas Provide support to the GPCH or CDH in interactions with external partners (e.g., regulatory authorities, key opinion leaders, data monitoring boards, advisory boards, patient advocacy groups), internal partners (e.g., clinical trial team, Medical Affairs, Commercial, Health Economics & Outcomes Research), and decision boards) Work with BR (Novartis Biomedical Research)/Translational Medicine) to drive transition of early development projects to Transition Decision Point and with Business Development, including target identification and due diligences Ensure career development of Program Reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for Global Clinical team Minimum Requirements: MD (or equivalent medical degree) required. Training in cardiology preferred Medical Board certification preferred. 4+ years Clinical practice experience (including residency) preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) required 5+ years of experience in clinical research or drug development from the pharmaceutical/biotechnology industry, preferably spanning clinical activities in phases I through IV 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrixed environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of Good Clinical Practice, clinical trial design, statistical analysis methodology, and regulatory/clinical development processes People management experience preferred, especially at the global level (this may include management in a matrixed environment) Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we-ll help you thrive personally and professionally:- Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Dublin (NOCC), Ireland Alternative Location 2 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Are you a highly skilled and ambitious medical professional with a passion for research? If so, we have an exceptional opportunity for you! Novartis, a world-class pharmaceutical company, is seeking a Clinical Development Medical Director - Renal to join our team in Switzerland. As a Research role, this position offers a unique chance to contribute to groundbreaking medical advancements in the field of renal medicine. About the Role Novartis is seeking a highly qualified Clinical Development Medical Director - Renal **80-100% to join our exceptional team in Switzerland or the UK. As a world-class pharmaceutical company, Novartis is dedicated to improving global health through groundbreaking research and innovative solutions. Responsibilities: Lead the clinical development activities for renal disease therapeutic area, ensuring flawless execution of clinical trials. Collaborate with cross-functional teams to design and implement clinical development plans. Provide medical expertise and guidance throughout the clinical development process. Successfully compete clinical trial protocols, investigator brochures, and informed consent forms. Determine appropriate safety monitoring and risk management strategies. Ensure compliance with all applicable regulatory and ethical guidelines. Contribute to the preparation and submission of regulatory documents. Analyze and interpret clinical trial data to support decision-making. Participate in scientific conferences and present clinical trial results. Requirements: Medical degree and experience in Nephrology or a related field. Proven experience in clinical development within the pharmaceutical or biotech industry. Strong knowledge of renal diseases and related therapies. Excellent understanding of clinical trial design and execution. Exceptional communication and interpersonal skills. Ability to work effectively in a cross-functional and multicultural environment. Strong leadership and project management abilities. Proficiency in English, both written and spoken. Novartis offers a unique opportunity for a CDMD to contribute to innovative research and make a significant impact on patients' lives. Joining our team means working with individuals who demonstrate exceptional problem-solving skills and a dedication to collaborative work in a dynamic and driven environment. At Novartis we are committed to fostering diversity and inclusion. We are an equal opportunity employer (EOE) and value the contributions of individuals from all backgrounds. We strive to provide a work environment that promotes fairness, respect, and equal opportunities for growth and development. We also understand the importance of reasonable accommodations and adjustments for individuals with disabilities. If you require any accommodations or adjustments throughout the application process, please let us know, and we will ensure that your needs are met. Join a leading organization committed to revolutionizing healthcare through advanced research and inventive solutions. Apply today and contribute to our impactful work! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are looking for a currently enrolled Master student and can offer the rare opportunity to write a Master's thesis in our Data Science and Analytics Department. The task in a nutshell: Define the Data architecture of a solution elaborated in a project leveraging existing patterns. About the Role Data Architect - Internship We are looking for a Data Architect Intern to join our project team. The ideal candidate will have a strong understanding of data flow diagrams, data modelling, and data dictionaries. They will be responsible for designing consistent and efficient storage, integration, and access to data across the development process. Preferred Start Date : ASAP Duration : 6-12 months Key responsibilities: Design and maintain data flow diagrams, data models, and data dictionaries. Develop and implement data integration processes to combine data from multiple sources into a unified view. Establish relationships between data entities and set rules and standards for integration and interoperability. Ensure efficient data management and effective analysis/reporting to support business goals. Collaborate with various departments to ensure data architecture aligns with organizational objectives. Work Arrangement : Hybrid Minimum Requirements: Education : Currently enrolled in a Master's Degree in Computer Science, Information Technology, or a related field. Experience/Professional Requirements : Proven experience in data architecture, data modelling, and data integration processes. Desirable Requirements : Experience with data governance and metadata management. Familiarity with data storage solutions and data management tools Skills: Business Architecture. (Relito, Immuta) Enterprise Architecture. (Colibra) Data Quality (Ataccama) Data Governance. Solution Architecture. (databricks on AWS) Languages : Proficiency in English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10032015 Mar 21, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: Novartis holds a rich development portfolio of small molecules ready to develop into innovative, patient centric, oral dosage forms. As a Drug Product Project Leader (DPPL) working on oral dosage forms, you will lead and manage formulation and manufacturing activities linked to pharmaceutical development for small molecules (New Chemical Entities; NCE). For this position, specific emphasis lies on bringing in-depth experience of pharmaceutical unit operations and related late-phase experience including scale-up and transfer to the commercial site. You will lead drug product teams during all stages of development with a specific focus on late clinical phases. You will be working on oral Small Molecules and in particular on enabling formulation approaches. You will use your strong communication, stakeholder management and influencing skills to effectively lead the drug product sub team and the transfer team in a matrix organization. Your expertise will facilitate the planning and execution of smart DoE and scale-up / transfer campaigns to establish robust manufacturing processes and stable drug products suitable for human trials and commercial supplies following ICH principles. About the Role Your responsibilities will include but are not limited to: You lead and manage all Drug Product (DP) related technical development activities for assigned projects and you represent DP project teams in Technical Research and Development (TRD) sub-teams based on your strong scientific and pharmaceutical development expertise. You lead, manage and support the DP and the transfer teams in line with Novartis values and behaviors. You build strong team spirit and promote knowledge exchange within and between teams. You motivate and coach team members for high performance. You formulate a sound DP project strategy incl. contingency planning and risk assessments as appropriate, involving functional experts, and you ensure alignment with Pharmaceutical Development department and other departments and functions inside and outside of TRD and 3rd parties as applicable. You ensure adherence to the scientific and project review process and through relevant scientific and project management governance boards You ensure creation of high quality and scientifically sound DP development documents enabling a strong CMC submission package, and act as author, reviewer or approver for development documents in accordance with operational procedures and guidelines. You contribute to the generation of registration dossiers, answer DP related questions in internal and external audits, and support Health Authority requests. What you-ll bring to the role: PhD in Pharmaceutical Sciences or relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 3 years of relevant technical experience in Development of oral Pharmaceutical Drug Products with proven experience in leading project teams in a matrix organization. Strong expertise in pharmaceutical oral dosage form development, manufacturing, and scale-up for formulations for Small Molecules including enabling formulations, manufacturing and IPC technologies, and scale-up principles. An understanding of material science principles, as applied to oral dosage forms, including the impact of physico-chemical properties of API and excipients on the drug product process and quality. Experience with application of Quality by Design and Quality risk management principles and tools as well as good working knowledge of regulatory guidelines relevant to Drug Product Development, validation, risk management, testing and stability, and new drug applications, together with technical writing and presentation skills. Ideally experience in applying data science, statistics, and DoE to enhance pharmaceutical development by providing a robust framework for data analysis, experimental design, and decision-making, leading to more effective and efficient drug development processes and documentation. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Role Purpose: Novartis holds a rich development portfolio of small molecules ready to develop into innovative, patient centric, oral dosage forms. As a Drug Product Project Leader (DPPL) working on oral dosage forms, you will lead and manage formulation and manufacturing activities linked to pharmaceutical development for small molecules (New Chemical Entities; NCE). For this position, specific emphasis lies on bringing in-depth experience of pharmaceutical unit operations and related late-phase experience including scale-up and transfer to the commercial site. You will lead drug product teams during all stages of development with a specific focus on late clinical phases. You will be working on oral Small Molecules and in particular on enabling formulation approaches. You will use your strong communication, stakeholder management and influencing skills to effectively lead the drug product sub team and the transfer team in a matrix organization. Your expertise will facilitate the planning and execution of smart DoE and scale-up / transfer campaigns to establish robust manufacturing processes and stable drug products suitable for human trials and commercial supplies following ICH principles. About the Role Your responsibilities will include but are not limited to: You lead and manage all Drug Product (DP) related technical development activities for assigned projects and you represent DP project teams in Technical Research and Development (TRD) sub-teams based on your strong scientific and pharmaceutical development expertise. You lead, manage and support the DP and the transfer teams in line with Novartis values and behaviors. You build strong team spirit and promote knowledge exchange within and between teams. You motivate and coach team members for high performance. You formulate a sound DP project strategy incl. contingency planning and risk assessments as appropriate, involving functional experts, and you ensure alignment with Pharmaceutical Development department and other departments and functions inside and outside of TRD and 3rd parties as applicable. You ensure adherence to the scientific and project review process and through relevant scientific and project management governance boards You ensure creation of high quality and scientifically sound DP development documents enabling a strong CMC submission package, and act as author, reviewer or approver for development documents in accordance with operational procedures and guidelines. You contribute to the generation of registration dossiers, answer DP related questions in internal and external audits, and support Health Authority requests. What you’ll bring to the role: PhD in Pharmaceutical Sciences or relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 3 years of relevant technical experience in Development of oral Pharmaceutical Drug Products with proven experience in leading project teams in a matrix organization. Strong expertise in pharmaceutical oral dosage form development, manufacturing, and scale-up for formulations for Small Molecules including enabling formulations, manufacturing and IPC technologies, and scale-up principles. An understanding of material science principles, as applied to oral dosage forms, including the impact of physico-chemical properties of API and excipients on the drug product process and quality. Experience with application of Quality by Design and Quality risk management principles and tools as well as good working knowledge of regulatory guidelines relevant to Drug Product Development, validation, risk management, testing and stability, and new drug applications, together with technical writing and presentation skills. Ideally experience in applying data science, statistics, and DoE to enhance pharmaceutical development by providing a robust framework for data analysis, experimental design, and decision-making, leading to more effective and efficient drug development processes and documentation. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10044172 Apr 09, 2025 Switzerland Summary The International MA team represents the voice of the International markets, with a focus on our top priority markets and addresses their needs across pre-launch, launch, life-cycle management and in-market. Responsible of key strategic areas within the International TA and deputize the Head of International Medical Affairs CRM in key leadership forums. Provides aligned input from the top priority International markets into IEP and is responsible for the implementation of the scientific communications and medical education strategy, as well as relevant medical standards in these markets. Supports the planning and execution at International for the medical/scientific engagement strategy (MSL / Field Medical Affairs strategy, medical education programs, scientific publication planning and Medical Expert network development) addressing and delivering strategic pre-launch and launch medical activities needs for patient, clinical, access and value to health care systems. Acts as a subject matter expert in the development of the overarching strategies for International, providing inputs during design and along the end-to-end execution of programs. Provides leadership and deep medical expertise across TAs, pivoting support based on business priorities. Acts a strategic partner to International Commercial, International Value & Access, Global, Regional and US MA, and Development. About the Role Key responsibilities: Lead the International Medical Affairs team for a particular disease area (Renal) including managing international medical directors (direct reports) and any medical directors on temporary rotation/assignment to the team. Oversee the medical affairs launch strategy for all priority programs in key International countries including transformational tactics such as: research/population health, innovative partnerships and integrated evidence plans. Partner with Medical Affairs organizations in key countries to ensure strong delivery focused on country needs. Advisor to plans for evidence generation, MSL / Field Medical Affairs strategy, medical education programs, scientific publication planning and Medical Expert network development with TAs. Co-own the development and implementation of innovative education and scientific communication plans for all brands for external stakeholders at International. Financial tracking to ensure timely and cost-effective development & execution of medical activities. Partner with Development, Global Medical Affairs (GMA), International Value & Access & International Commercial and Launch Strategy (CLS) to shape launch portfolio and diversify evidence to achieve broad access at launch and to enhance impact on clinical practice for priority programs. Represent International Medical Affairs around prioritized portfolio with internal (GMA, Development, Biomedical Research etc.) and external audiences, in collaboration with CLS including the investment, medical and regulatory communities, as well as pharmaceutical or biotechnology industry collaborators/partners. Represent -the voice of the patient- internally and evaluate factors relevant to a patient-s informed decision making. Ensure that Patient Access programs are supported for all brands within International Medical Affairs and delivered with full compliance. Provide direction and input into the development and implementation of successful reimbursement and market-access strategies. Provide input to shape Field Medical Strategies, develops, and executes Field Medical plans, ensure implementation of key Field Medical initiatives, e.g., insight gathering, sharing and translation into action, development and conduct of trainings on disease area and medical/ scientific knowledge, and guides MSL resourcing and deployment.Provide proactive medical input to asset lifecycle management to consider new therapeutic opportunities. Ensures International Medical Affairs activities are designed and executed in compliance with company policy guidelines and highest medical quality standards. Essential requirements: MD (Preferred) or PhD/PharmD in Health Sciences. Specialist Degree or specialist qualification related to discipline for which is responsible is an advantage 7+ years in Pharmaceutical Industry experience in Medical Affairs and/or Clinical Development Strategic mindset and able to establish credibility and influence across a range of diverse stakeholders in a matrix organization to drive change Deep understanding of health care systems and key external stakeholders. Agile mindset & ability to lead in an agile organization across Disease Areas Understands unmet medical needs, generates the right evidence to fulfil them, uses innovative, multichannel communication formats for effective evidence dissemination Ability to truly collaborate across functions and markets: serve-partner-co-create. Credibility as peer expert with external stakeholders Able to navigate in an environment of shared outcomes and cross-business accountabilities. Critical thinker and with ability to navigate uncertainty without major supervision. Strong track record of delivery focus for time and quality in medical affairs projects. Successful development and implementation of innovative programs and processes Desirable requirements: Highly preferred: Significant medical affairs pre-launch and launch experience in major markets (ie Germany, China, Japan). Experience in renal disease. Experience in developing and executing -Best in Class- processes at scale Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Finance Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We are looking for a GCP Bioanalysis Senior Scientist in the Translational Medicine Drug Disposition Bioanalytical group. The role involves using bioanalytical knowledge and lab/instrument skills to develop, validate, and analyze clinical samples for the company's novel modality biologics portfolio. Responsibilities include independently designing and validating assays, performing sample analysis, processing data, and evaluating results. As Senior Scientist you will also contribute to health authority documents, maintain lab equipment and records, and mentor team members. The ideal candidate has a college/university degree in biological sciences, experience in regulated biologics bioanalysis, proficiency in various biological techniques, and the ability to work independently and meet deadlines. About the Role In the Senior Scientist role, you will use your knowledge of bioanalytics and lab/instrument skills to develop, validate and analyze clinical samples focusing on our novel modality biologics portfolio. Key responsibilities: Independently designing, developing, and validating assays, and performing sample analysis using biological techniques for PK, PD and immunogenicity following SOPs and guidelines. Being responsible for all assigned study/lab/project activities, and providing input to bioanalytical strategies. Data processing, evaluating results, interpreting data, and drawing relevant conclusions. Critically analyzing data on study and project levels. Conducting lab activities and keeping timely raw data records in accordance with company and health authority guidelines. Preparing study protocols, reports, and contributing to health authority documents. Maintaining high level of competence on routinely used laboratory equipment and/or LIMS systems. Evaluating and setting up new technologies as they are introduced to the lab. Contributing to the general lab environment, including instrument maintenance, writing/updating templates and SOPs, software validation activities, ordering supplies, etc. Coaching and mentoring in a matrix team environment. Essential requirements: College/university degree in biological related sciences or equivalent, with 3+ (Masters) or 5+ (Bachelors) years of experience. Experience in regulated biologics bioanalysis preferred. Strong laboratory skills with proficiency in several biological techniques (ELISA, ECL, PCR, etc.) and their associated software. Ability to work with minimal supervision and organize work across multiple projects to meet timelines Eagerness to take on additional responsibilities when required; flexibility to adapt to changing priorities and strategies. A collaborative spirit and willingness to mentor/coach peers Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Global Program Safety Lead – RLT Primary Location: Basel, Switzerland (80-100%) Alternate Location: Barcelona, Spain Working model: All locations have a hybrid working model (which requires 12 days per month in the office) Note: Novartis is not able to offer relocation support for this role. Please only apply if one of these locations is accessible for you. About this role: Our Global Program Safety Lead excels as a scientific safety leader within the Oncology Medical Safety organization and is part of our (RLT) Radioligand Therapy team. Join us and you will make a significant impact on patients' lives and contribute to Novartis' overall success through robust safety evaluation expertise and medical innovation. About the Role Key Responsibilities: Safety Input and Team Participation: Provide expert safety input to the clinical development program for assigned projects/products and actively participate in the Global Program Team (GPT), Global Clinical Team (GCT), and Clinical Trial Team (CTT). Responsible for managing safety issues from the formation of the GPT through Life Cycle Management Signal Detection and Safety Management: Oversee overall signal detection, monitoring, evaluation, interpretation, and appropriate management of safety information, based on data from all relevant line functions, post-marketing data, and other sources Documentation and Record Keeping: Ensure proper documentation, tracking, and record-keeping of medical safety activities for assigned compounds Regulatory and Professional Inquiries: Respond to inquiries from regulatory authorities or healthcare professionals regarding safety issues Safety Strategy Preparation: Lead the preparation of the safety strategy for health authority responses and collaborate with other project team members Departmental and Functional Goals: Contribute to and often lead the development of departmental and functional/business unit goals and objectives Role Requirements: Medical Degree or equivalent is preferred PhD, PharmD or equivalent graduate level health care professional degree required 3-5 years of experience in Oncology Minimum 7 years progressive experience in drug development in a major pharmaceutical company (of which 5 years in a global position), including 5 years in safety at a medical position Strong experience in drug development, clinical trial methodology, regulatory requirements, scientific methodology, statistics and writing of publications Expertise in preparing or contributing to preparation of clinical safety assessments and regulatory reports/submissions involving safety information – to include NDA submission documents Experience with contributing to Safety Science Strong experience in leading cross-functional, multi- cultural teams Strong experience with (safety or others) issue management Desirable Skills: Experience in Radioligand and/or Nuclear Medicine Specialty Board Certification Languages: Fluent English (both spoken and written) is essential Additional languages are an advantage Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10047948 Apr 13, 2025 Switzerland Summary The Lead Central Monitor supports the Central Monitoring Head to drive excellence in clinical trial monitoring by establishing and delivering a state-of-the-art Central Monitoring (CM) capability at Novartis in Global Clinical Operations (GCO). The Lead CM is responsible for managing a team of Central Monitors, for developing central and site monitoring strategies, ensuring that the configuration of the CM platform aligns with strategic needs, is consistent with identified indications, program, and study risks, in alignment with the IQRMP, to ensure appropriate trial data surveillance in order to deliver quality and integrity of the trials- clinical data Apply today and we can thrive together! This role will be based in Basel, Switzerland, Dublin, Ireland or London, UK in a hybrid working approach. About the Role Major accountabilities but not limited to: Support the establishment and implementation of a CM function at Novartis, including processes, tools, and governance frameworks to support RBQM. Manage and mentor a team of CMs, fostering professional development, ensuring alignment with CM processes, and maintaining high performance across the team. Partner with the CM Head to set, refine and implement the CM strategy, contributing to the continuous improvement of Risk-Based Monitoring (RBM) processes across the organization. Oversee the analysis and interpretation of CM dashboards and data visualization tools to identify and contextualize risk signals and ensure accurate root cause analysis and mitigation actions Provide strategic input during protocol development and study setup to ensure comprehensive risk identification and alignment with RBQM objectives and processes. Ensure appropriate trial data surveillance to deliver quality and integrity of the trials- clinical dat Act as a key stakeholder in the evaluation, adoption, and improvements of the CM tools and technologies, ensuring effective integration into workflows. Drive innovation in the use of analytics, visualization, and data-driven techniques to enhance risk identification and monitoring capabilities. Education & Experience: University degree in life science, business or operations; Advance degree preferred 7 years of recent pharmaceutical industry experience, with previous experience in clinical research, in a Pharmaceutical Industry or CROs. Strong clinical experience with excellent understanding of clinical trial development and risk management processes and the management of clinical trials (including trial design, protocol development, study start-up, patient recruitment and study close-out). Specific Central monitoring / monitoring experience (hands-on experience with Key Risk Indicators -KRIs- review, centralized monitoring and quality tolerance limits -QTLs-) are strongly preferred, Experience in implementing or working within Risk-Based Quality Management (RBQM) and adaptive monitoring frameworks 3 years of recent experience in people management and/or team leadership. Strong leadership and people management skills in global setting and proven ability to develop high performing teams and diverse profiles including manager of manager experience. 5 years comprehensive experience in monitoring (central, site), clinical data analytics, data management activities or equivalent. Knowledge of overall clinical trial -planning and execution process, understanding of the protocol, study associated risks and their significance, and the risk management process. Proven experience in developing, implementing, and maintaining quality control documentation for remote/central monitoring activities, ensuring data integrity, completeness, and accuracy. Thorough understanding of the international aspects of drug development process, including expert knowledge of international standards (GCP/ICH), health authorities, and Novartis standards. Advanced critical thinking and analytical skills to understand/analyze/interpret complex clinical and operational data and provide insight into risk signaling, trends, and outliers in data Ability to interpret study protocols, assess study-associated risks, and understand operational and quality implication. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team-s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Dublin (NOCC), Ireland Alternative Location 2 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10038818 Mar 27, 2025 Switzerland Summary Our Immunology Disease Area in Biomedical Research division in Novartis is dedicated to world-class research and finding breakthroughs in treatments for millions of patients worldwide suffering from Immunological conditions and diseases. We are currently seeking a senior level Molecular Pathologist with either a Medical or Veterinary doctoral background and a Pathology certification, to join our teams and lead a lab in the Immunology Disease area and help us tackle some of the most challenging unmet needs. About the Role Job Description You will be part of a cross-disciplinary team, working with various labs in Immunology. A strong emphasis for this role is placed in effective teamwork, networking across teams, and development of successful partnerships with academic leaders worldwide. Your responsibilities will include but not be restricted to: Lead an experimental pathology lab within the Molecular Pathology group, in Immunology Translational Research. Use tissue samples from healthy humans, patients suffering from immunological diseases and corresponding animal models for: - Disease understanding - Target validation - Biomarker discovery (pathway-based and pharmacodynamic) Implement spatial omics technologies Use of state-of-the-art imaging modalities and digital image analysis to address key scientific questions Provide pathology expertise for tissue biomarkers in clinical studies Work closely with multidisciplinary project teams in discovery and translational research. Minimum requirements - What you will bring to the role: MD or DVM with relevant human or veterinary pathology experience; plus PhD-level research background You must be a Board-certified Pathologist or Veterinary Pathologist strong Experimental Pathology background/expertise Experience in animal mechanistic and disease models as well as human biosamples Strong background and hands-on expertise in immunohistochemistry and in-situ hybridization, including method development Strong leadership skills - experienced team leader with direct reports, including professional development of team members Excellent presentation and communication skills in English (oral and written), innovative thinking and project management skills Desirable: Prior experience in spatial omics will be an advantage Knowledge of or interest in autoimmune and dermatological diseases is highly desirable *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10044981 Mar 27, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated, passionate scientist and leader specialized in RNAi therapeutics to join the xRNA group within Biologics Research Center (BRC) in Basel, Switzerland as Principal Scientist, xRNA. The xRNA team strives for excellence and drives a diverse portfolio of siRNA assets and platform innovation to attenuate gene expression via RNAi. Our xRNA team is dedicated to excellence, constantly pushing for novel advancements in our diverse portfolio of siRNA assets and platform strategies to modulate gene expression through RNAi. The team's collaborative efforts with Disease Area groups, Global Discovery Chemistry, and Discovery Sciences are focused on expanding the application of RNAi beyond the liver. About the Role As Principal Scientist in xRNA Therapeutics, you will have an opportunity to join the Biologics Research Center (BRC) as a leader at the cutting edge of innovative medicine development to improve patient lives. BRC builds the biologics pipeline in collaboration with Biomedical Research Disease Areas via a breadth of technologies for discovery of antibody, protein, gene therapy and RNA-based therapeutics. The successful candidate will have a strong research track record in drug discovery and will provide key expertise in the development of next generation RNA based medicines and their acceleration to patients. They will lead boldly and collaborate effectively across therapeutic and functional areas to advance our growing RNA portfolio across various diseases states. Key Responsibilities: Lead a team of highly talented scientists on the Basel site responsible to drive RNAi based therapies to patients via design, screening and characterization. Establishes mid- and long-term goals, plan of action and implementation for the local xRNA team in line with global strategy for xRNA and Biologics Research Center Develops and implements strategy for next generation extrahepatic RNAi for various disease areas including renal, cardiometabolic, and cardiovascular. Co-leads RNAi drug discovery and development in partnership in Global Discovery Chemistry and Disease Areas. Collaborate with downstream development colleagues to bring lead candidates towards full development. Collaborates and coordinates activities with other global BRC and functional groups Offers innovative approaches to scientific questions and troubleshooting efforts. Identifies Disease Area-s unmet needs and collaborate for a novel therapeutic solution. Role Requirements: PhD level scientist with 5 years of relevant experience, recognized both internally and externally as an expert in RNAi Prior experience with drug discovery focused on RNAi design, screening, and characterization Deep knowledge of RNAi chemistry and biology applied to lead optimization of therapeutic candidate A proven track record of success as judged by publications and patents Knowledge in the application of RNAi to biology in the areas of renal metabolic diseases is desirable Highly collaborative spirit to accelerate programs to clinic; good communication skills, creativity, and multi-tasking in a fast-paced environment. Excellent, oral and written communication skills Experience with extrahepatic/kidney targeting of RNAi is a preferred *Restrictions on flexible working arrangements may apply and will be discussed at interview if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10040719 Apr 04, 2025 Switzerland Summary This role will act as liaison between Finance, DDIT, and Digital Finance teams to ensure project and solution alignment & establish governance processes. Responsible for Data Management governance across various tools, systems, and products in Digital Finance. About the Role Your responsibilities include, but not limited to: Act as the primary connection across Finance, DDIT and Digital Finance teams to ensure overall solution and Project delivery alignment. Understanding of data flows in the Business, Planning & Analysis (BPA) world (commercial) Governance of the master data hierarchies across tools/systems/products in Digital Finance Set up process for this governance Liaise with business (Corp, US, International, Regions, Countries) to collect all requests and perform the assessment Governance of actuals and planning versions published in the tools, as well as the calendars Liaise with business (Corporate, US, International, Regions, Countries) to understand the processes and dependencies Might extend to all units for certain reports/processes Performs and maintains confidentiality assessment of data, keeping up with considerations coming from the different units, e.g. the Swiss data restrictions and the impact on the tools / Data confidentiality reassessment triggered by the 141 changes and Sandoz spin-off Generates and maintains the guidelines for user access, establishing with the units which users should have access to which data, and harmonizing across D&T Is in contact with the EDO office, ensuring Digital Finance complies with the Finance EDO and EDM guidelines Understands data sources (FRA, LDC, etc.) and can establish links with both teams to anticipate changes that may impact data security, master data or governance What you'll bring to the role: Relevant degree (e.g.: Business, Finance), or demonstrated comparable experience in business, management or engineering. Proficiency in English required - spoken & written, other languages is an asset. Demonstrated Project Management experience - certification in project management is desirable. Very strong process orientation. Experienced in Data management using industry standard tool. Technical orientation, good understanding of data bases and systems (preferably for Finance Data Reporting & Analytics). Proven experience working with technical teams/developments. Good problem solving, hands-on and analytical - a strong team player with solution orientated and initiative-taking mindset. Experience working in multi-functional settings, across multiple organizational level Ability to deal with highly complex environment, translating complexity into actionable recommendations Good analytical skills linked with conceptual thinking capabilities Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Finance Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area Audit & Finance Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Expert to support Analytical Research & Development (ARD). ARD sits within the Global Technical R&D department of Global Drug Development and plays an essential role in the characterization and analysis of Small Molecule Drug Substances and Drug Products from the time they leave the discovery laboratory until they are transferred to Commercial Production. We are looking for a highly motivated, experienced Analytical Expert with a strong background and experience in parenteral development to join our team. Expertise in RLT, peptide analytics and parenteral dosage form is required. About the Role Your main responsibilities: Plan, interpret and report results of scientific experiments for timely supply of drug substances (DS) and drug products (DP). Write & review analytical documents (e.g Analytical methods, Specifications, Validation reports, Stability reports, Batch records for stability and release testing) and align the corresponding activities within a global project team. Drive method development for peptide drug substances and RLT Drug product. Manage interactions with internal and external stakeholders, including outsourced activities to CROs by providing scientific and technical guidance whenever necessary. Proactively identify scientific, technological and GMP challenges, propose creative solutions and communicate key issues to the Analytical Project Leader or respective technical project team. Work according to appropriate SOPs, GMP, Quality Directives, Health and Safety & internal Novartis guidelines. Provide valuable input to the analytical CMC documents and support regulatory submissions. Drive, lead, and manage analytical activities including impurity profiling related to the analytical development of RLTs compounds (e. g. method development, validation, stability, and release testing). Provide scientific guidance to the cross-functional and global project teams and thereby scientifically driving our exciting RLT portfolio. Display a collaborative and inspired attitude within project teams and our stakeholders and partners is key. Good understanding and awareness of regulatory guidelines for analytical development What you’ll bring to the role PhD in analytical chemistry or equivalent At least 5 years experience in the pharmaceutical industry with a track record in GMP activities for development or marketed products. Profound expertise in documentation writing (Stability Report, Validation, IND IMPD modules etc) Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Advanced knowledge of laboratory and/or technical tools (e.g. HPLC, LC-MS, Quality management systems, statistical evaluation tools ...) Good knowledge of commonly used software and computer tools. Excellent scientific/technical writing skills. Eager to develop new methods and assess new analytical techniques. Proven leadership in guiding and mentoring colleagues Strong coordination skills, collaborative spirit, self-driven attitude, high level of learning agility. Strong quality focus Excellent communication and role model skills Fluent in English (oral and writing) Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis is at the forefront of medical research and bringing innovative and life changing medicines to millions of patients. Animal research is key to many of the great medical advances of today and animals play an integral part in the discovery and development of innovative, safe and life-saving medicines for patients. The Basel Head of Animal Welfare and Integrity Assurance (AW&IA) will lead, manage, and evolve the internal animal care and use program oversight for Biomedical Research Basel. About the Role Novartis upholds the highest standards and ethics of Animal Welfare and research, with steadfast commitment to the 3Rs principles (Reduction, refinement, Replacement), as well as introducing further improvements including the ‘4th R’ of Responsibility and our Biomedical Research sites all earning independent, international Gold Standard accreditation from the Association for Assessment and Accreditation of Laboratory Care (AAALAC). The Head of Animal Welfare and Integrity Assurance will ensure that all work involving research animals at Biomedical Research Basel is in compliance with Swiss laws and the Novartis Animal Welfare policies and standards. The role will include responsibilities such as liaising on behalf of Novartis Biomedical Research with regulatory authorities, accreditation bodies, and external groups and championing animal welfare and the 3Rs, as well as advocate for the critical role of animals in biomedical research. Your Responsibilities will include but not be restricted to: Lead internal oversight of the Biomedical Research Basel animal care and use program, including acting as site’s Lead Animal Welfare Officer and key contact for all in vivo users, regulators, and accreditation bodies. Direct Biomedical Research Basel AW&IA activities as Site Head to achieve efficient, consistent, compliant, and continuous improvement of animal care and use oversight operations, including: management and support of the license review and animal number reporting process post-approval monitoring program semi-annual inspections and program reviews investigation of reported animal welfare concerns/non-compliances ensure appropriate management of the Animal Welfare Body meetings as chair and all related preparation, facilitation, administration and follow-up actions serve as key contact to in vivo leadership including to the Institutional Official, Basel Pharmacology Council, and Basel Leadership Team support the development of the new animal management system Serve as named main point of contact for regulatory and accreditation needs, including both announced and unannounced inspections, communication with the Cantonal and Federal veterinary authorities, for documentation/information (e.g. lead AAALAC program description and site visits), and reporting out to agencies on applicable timelines (e.g. annual reports, ad hoc event reporting) Lead and manage direct reports in local AW&IA team, ensuring their development and appropriate time management. Act as a key contributor to the Global AW&IA team representing the Basel site to the Ethical Review Council, Global 3Rs Working Group and Global Risk Review teams Promote the 3Rs via leadership or delegated leadership of the local 3Rs Working Group including promotion of the 3Rs Awards programs and Innovation in 3Rs Granting program Together with colleagues in Public Affairs, promote openness and education about the continued need for and value of animal research through internal and external collaborations and communication, including participation in direct political stakeholder engagement. Minimum Requirements – what you will bring to the role: Education : University degree (PhD, Vet med, Med) in biology, veterinary medicine or medicine. Special knowledge in laboratory animal science and alternative methods. Authority approved study director role in Switzerland Experience in regulatory compliance and working as an Animal Welfare Officer in Switzerland, leading an IACUC or animal welfare body Experience: At least 5 years experiences in animal experimentation and leading and managing personnel in an in-vivo research environment Experienced in leading and managing a team of Direct and indirect Reports in a complex matrixed research and operations pharma industry environment Knowledge in public relations and Professional experience in communicating about and supporting advocacy efforts for the need for animal research to internal and external audiences highly desirable Experience working collaboratively with regulators and accreditation bodies Experience in supporting 3Rs (reduce, refine, replace animal studies) programs Languages: English and German fluent, proficiency in e.g. French would be of advantage. Desirable Continuous improvement skills and experience in using evidence to design and test improvements to programs and processes, including advancing AI and automation in licensing and reporting Experience in assessing animal care and use programmes requiring larger laboratory animal species, including Non-Human Primates (NHP), Pig, and Dog Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Central Monitor (CM) plays a key role in overseeing and supporting clinical trials through centralized monitoring activities. This role ensures data quality, identifies potential risks, and enhances trial oversight by leveraging data analytics and risk-based monitoring strategies. The CM collaborates with cross-functional teams to ensure compliance with study protocols, regulatory requirements, and Good Clinical Practice (GCP) guidelines. The CM will play a vital role in the study Risk-Based Quality Management process. This role is key to detect any study related risk/issue(s) within the scope of study RBM strategy. The CM will be involved early during clinical trial lifetime, working alongside the Risk Surveillance Lead and others to support risk identification, risk assessment, definition of risk oversight measures (Key Risk Indicators - KRIs). Apply today and we can thrive together! This role will be based in Basel, Switzerland, Dublin, Ireland or London, UK in a hybrid working approach. About the Role Major accountabilities but not limited to: Implement and execute centralized monitoring strategies to support clinical trial oversight. Conduct ongoing central monitoring analysis of clinical trial data to detect trends and signals. Perform data surveillance via the CM platform, identifying potential site or trial risks. Collaborate with Lead Central Monitor and study teams to refine and implement risk-based monitoring plans. Generate and summarize findings within the CM platform and lead the communication of results to study teams.. Contribute to GCO understanding of impact of findings to data quality. Ensure timely documentation of monitoring activities and findings. Document findings, escalate critical risks, and support follow-up actions. Collaborate with cross-functional study teams, including Risk Surveillance Leads, Study Leaders, Data Managers, and Clinical Scientific Leaders, to ensure robust risk mitigation plans are in place and effectively executed. Advise on the design and optimization of KRIs and thresholds to enhance the efficacy of Central Monitoring efforts. Support the continuous improvement of centralized monitoring methodologies. Ensure adherence to regulatory requirements, SOPs, and Good Clinical Practice (GCP) guidelines. Contribute to training and knowledge-sharing initiatives within the Central Monitoring team. Education & Experience: University degree in life science, business or operations ≥ 5 years of recent pharmaceutical industry experience, with previous experience in clinical research, in a Pharmaceutical Industry or CROs. Strong clinical experience with excellent understanding of clinical trial development and risk management processes and the management of clinical trials. Specific central monitoring / monitoring experience are strongly preferred. ≥ 3 years comprehensive experience in monitoring (central, site), additional experience in clinical data analytics, data management activities or equivalent is preferable. Specific Central monitoring / monitoring experience (hands-on experience with KRIs review, centralized monitoring and quality tolerance limits -QTLs-) are strongly preferred. Knowledge of Risk-Based Quality Management (RBQM) and adaptive monitoring principles. Knowledge of overall clinical trial management process, understanding of the protocol, study associated risks and their significance, and the risk management process. Thorough understanding of the international aspects of drug development process, including expert knowledge of international standards (GCP/ICH), health authorities, and Novartis standards. Critical thinking and analytical skills to understand/analyze complex data and provide insight into risk signaling, trends, and outliers in data. Strong analytical and critical thinking skills with the ability to interpret complex clinical and operational data, recognize patterns, and identify potential risk signals or issues. Strong understanding of clinical metrics and trend analysis; experience managing operational insight at site level. Excellent communication and coordination skills. Strong capability in working in a Global/Country matrixed environment. Organizational awareness, including significant experience working cross-functionally. Strong technical, analytical and quantitative problem-solving skills. Technical ability to use the relevant technology and risk-based tools/platforms effectively. Data and Digital expertise: experience working with e-databases, clinical and/or project management planning and reporting and analytics systems. Understanding team dynamics: recognizing the diverse talents, personalities, and working styles within a team to create a connected and productive work environment. Experience in transformation, leveraging AI and analytics Ability to understand and navigate diverse cultural contexts. Fluent English languages skills Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) ​ Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Director, Strategy & Operations for Corporate Communications will play a pivotal role in driving the success of the Corporate Communications team. This role will bring a strategic mindset and act as a trusted advisor to the Global Head of Corporate Communications, leveraging competitive intelligence, business insights, and data-driven analyses to shape and execute strategies that drive competitive advantage and business outcomes. They will also foster collaboration and innovation across teams and ensure operational excellence. About the Role Key Responsibilities: Provide strategic leadership as a member of both the Corporate Communications leadership team and the Chief of Staff’s leadership team, shaping priorities, driving cross-functional alignment, and advancing innovation to maximize the function’s impact and efficiency. Partner with the Global Head of Corporate Communications to co-develop and execute a forward-thinking strategy that advances the function’s objectives, leveraging competitive and business intelligence to deliver differentiation and drive competitive advantage. Lead planning, resource allocation, and the establishment of processes to ensure the Corporate Communications team’s efficiency and alignment with business priorities. Define and implement metrics to measure outputs and link them to business outcomes, ensuring resources and efforts are optimized. Develop and deliver strategic internal communications, including town halls and key updates, serving as a business partner to the Global Head of Corporate Communications and promoting alignment across internal and external stakeholders. Plan and execute high-impact leadership team meetings, team-building activities, and planning sessions to strengthen strategic alignment and drive organizational goals. Identify and implement opportunities to build new capabilities and processes that enhance the team’s ability to deliver against its mission. Oversee the management of the Corporate Communications budget, ensuring resources are allocated effectively and aligned with strategic priorities. Cultivate strong relationships across Corporate Affairs, company functions/units, and external partners to align strategies, share insights, and capture synergies that enhance business outcomes. Support the Global Head of Corporate Communications and Chief of Staff on various strategic projects and tasks, and participate in cross-functional projects, as needed Essential Requirements: Bachelor’s degree required. Many years of experience suggested, Communications expertise required. Experience in delivering high quality strategic insights and impactful contributions to key projects, aligned with the function’s objectives. Ensures proactive and efficient management of processes, ensuring timeliness and high-quality execution. Provides evidence of measurable success in fostering a culture of high performance, innovation, and collaboration. Effective optimization of processes, resource allocation, and financial management. Strong matrix management and influencing skills to manage complex challenges and opportunities. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary -Responsible for a consistent, cross-functional brand strategy shaping and implementation, for all assets having moved from Global to International TA until the handover to IBBI. Will evolve globally created early brand strategies, such as the Integrated Product Strategies (IPS) into a competitive, truly cross-functional launch plan that is fit-for-purpose for core IMI markets and sets a foundation of launch success for Novartis’ next blockbusters. (International) -Leads strategic, cross-functional decisions for International and above-brand strategic initiatives, incl. partnerships, policy shaping, and for launched assets, will monitor and respond to major events and competitive landscape developments. (International) -Close interaction with core IMI markets, collaboration with MAP and CE&E teams to shape launch deliverables and TA-relevant customer experiences/ journeys and campaigns/ content for major IMI markets, and with respective IM-US counterpart to ensure consistent brand positioning worldwide, leverage learnings and transferable practices. (International) -Leads, manages and develops the overall performance of the TAs current and future product portfolio and deliver sales and profits within agreed budgets. (Region/cluster/country) -Leads and develops a high-performing sales and marketing team and build effective and enduring business relationships with key customers/ stakeholders. (Region/cluster/country) -Typically leads a medium to large revenue country organization, covering both sales and marketing activities, with responsibility to drive performance and develop operational strategy for their organization. (Region/cluster/country) About the Role Our ambition is to be recognized as the #1 Oncology company in international markets and a successful RLT portfolio, is central to this ambition. The Executive Director International, Actinium , plays a pivotal role in building an end-to-end brand strategy, creating a vision, International strategy aligned with the GPT and across major international markets. As an enterprise leader, the ED will focus on the top three countries (Germany, Japan, and China) and Regions, collaborating with commercial insights on the Actinium programs and the successful launch of Actinium to achieve blockbuster status with over $1 billion in sales across two indications, thereby making a significant impact on patients' lives. The incumbent will collaborate closely with Global Drug Development (GDD), International Medical Affairs, Value & Access, Strategy & Growth, and Customer & Market Activation teams to drive consistent strategy development and execution. This role also leads the commercial team, fostering a culture of innovation, collaboration, and execution excellence. Key Responsibilities Collaborate closely with GDD to influence trial designs, go/no go criteria, TPP & Integrated Evidence Plan and maximize commercial attractiveness & patient access for Actinium indications. Lead through critical stages of new product development, from assessment to commercial strategy to launch readiness with a deep understanding of scientific principles and a strong business acumen. Lead the development and execution of comprehensive integrated plan, including, product positioning, differentiation, pricing scenarios and scientific message to maximize market penetration and Actinium growth. Analyze market trends and conduct extensive market research, capturing perspective from customers, deeply understanding market dynamics, competition. Use data-driven insights to inform demand and strategic decisions. Develop and partner with the top 3 countries (China, Japan, and Germany) to create robust strategic plans, ensuring meticulous execution and performance measurement. Continually collect and integrate feedback from leading countries and regions to refine and enhance brand strategy and positioning. Effectively build, refine and communicate Actinium vision and strategic goals to senior leaders, including the International Leadership Team (ILT), General Managers (GMs), and regional heads. Foster a customer-centric mindset within the international and country teams, focusing on personalizing experiences to extend patient reach and commercial impact. Build a team that attracts, within the Actinium brand team, fostering cross-functional collaboration and innovation. Essential requirements: Scientific Expertise & Business Acumen: strong scientific background with a deep understanding of drug development, commercialization strategies, and market dynamics, with a sharp business acumen. With either an advanced degree in the sciences -- or 5+ years’ experience working with development teams and commercial launch experience in oncology, especially in managing solid tumors. +15 years of commercial experience across various functions, demonstrating a broad and deep understanding of the commercial landscape. Proven track record of successful international launches, with commercial leadership experience and therapeutic area (TA) leadership in large markets. Proficient in translating scientific data into differentiated brand value propositions, enabling impactful launches across pre-launch through lifecycle management (LCM) stages. Experience with high-performing/high-growth brands or markets, with a clear understanding of key drivers that influence shifting customer and patient behaviors to ensure successful asset launches. Strong track record in collaborating and partnering with cross-unit, cross-functional & key markets to achieve strategic and performance targets. Leadership Capabilities: Proven ability to manage and drive performance, ensuring targets are met and exceeded in challenging markets. Demonstrated ability to lead and inspire teams, drive cross-functional collaboration, and think strategically in dynamic environments. Focuses on larger, longer-term issues, and creates plans and strategies. Comfortable in navigating the matrix and people related organizational dynamics. Establish credibility & influence across diverse stakeholders and able to navigate in an environment of shared outcomes and cross-business accountabilities. Demonstrates enterprise leadership, balance diverse stakeholders and conflicting priorities to drive results. Empowered teams to execute efficiently, through the layers of organization and across geographies. Clearly and effectively communicates with senior stakeholders (both internal &external)– to align on vision, purpose & goals. Generates trust, builds credibility and drives engagement with people and stakeholders. Location: This role is based in Basel, Switzerland Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10047378 Apr 14, 2025 Switzerland Summary -Responsible for a consistent, cross-functional brand strategy shaping and implementation, for all assets having moved from Global to International TA until the handover to IBBI. Will evolve globally created early brand strategies, such as the Integrated Product Strategies (IPS) into a competitive, truly cross-functional launch plan that is fit-for-purpose for core IMI markets and sets a foundation of launch success for Novartis- next blockbusters. (International) -Leads strategic, cross-functional decisions for International and above-brand strategic initiatives, incl. partnerships, policy shaping, and for launched assets, will monitor and respond to major events and competitive landscape developments. (International) -Close interaction with core IMI markets, collaboration with MAP and CE&E teams to shape launch deliverables and TA-relevant customer experiences/ journeys and campaigns/ content for major IMI markets, and with respective IM-US counterpart to ensure consistent brand positioning worldwide, leverage learnings and transferable practices. (International) -Leads, manages and develops the overall performance of the TAs current and future product portfolio and deliver sales and profits within agreed budgets. (Region/cluster/country) -Leads and develops a high-performing sales and marketing team and build effective and enduring business relationships with key customers/ stakeholders. (Region/cluster/country) -Typically leads a medium to large revenue country organization, covering both sales and marketing activities, with responsibility to drive performance and develop operational strategy for their organization. (Region/cluster/country) About the Role Our ambition is to be recognized as the #1 Oncology company in international markets and a successful RLT portfolio, is central to this ambition. The Executive Director International, Actinium , plays a pivotal role in building an end-to-end brand strategy, creating a vision, International strategy aligned with the GPT and across major international markets. As an enterprise leader, the ED will focus on the top three countries (Germany, Japan, and China) and Regions, collaborating with commercial insights on the Actinium programs and the successful launch of Actinium to achieve blockbuster status with over $1 billion in sales across two indications, thereby making a significant impact on patients' lives. The incumbent will collaborate closely with Global Drug Development (GDD), International Medical Affairs, Value & Access, Strategy & Growth, and Customer & Market Activation teams to drive consistent strategy development and execution. This role also leads the commercial team, fostering a culture of innovation, collaboration, and execution excellence. Key Responsibilities Collaborate closely with GDD to influence trial designs, go/no go criteria, TPP & Integrated Evidence Plan and maximize commercial attractiveness & patient access for Actinium indications. Lead through critical stages of new product development, from assessment to commercial strategy to launch readiness with a deep understanding of scientific principles and a strong business acumen. Lead the development and execution of comprehensive integrated plan, including, product positioning, differentiation, pricing scenarios and scientific message to maximize market penetration and Actinium growth. Analyze market trends and conduct extensive market research, capturing perspective from customers, deeply understanding market dynamics, competition. Use data-driven insights to inform demand and strategic decisions. Develop and partner with the top 3 countries (China, Japan, and Germany) to create robust strategic plans, ensuring meticulous execution and performance measurement. Continually collect and integrate feedback from leading countries and regions to refine and enhance brand strategy and positioning. Effectively build, refine and communicate Actinium vision and strategic goals to senior leaders, including the International Leadership Team (ILT), General Managers (GMs), and regional heads. Foster a customer-centric mindset within the international and country teams, focusing on personalizing experiences to extend patient reach and commercial impact. Build a team that attracts, within the Actinium brand team, fostering cross-functional collaboration and innovation. Essential requirements: Scientific Expertise & Business Acumen: strong scientific background with a deep understanding of drug development, commercialization strategies, and market dynamics, with a sharp business acumen. With either an advanced degree in the sciences -- or 5+ years- experience working with development teams and commercial launch experience in oncology, especially in managing solid tumors. +15 years of commercial experience across various functions, demonstrating a broad and deep understanding of the commercial landscape. Proven track record of successful international launches, with commercial leadership experience and therapeutic area (TA) leadership in large markets. Proficient in translating scientific data into differentiated brand value propositions, enabling impactful launches across pre-launch through lifecycle management (LCM) stages. Experience with high-performing/high-growth brands or markets, with a clear understanding of key drivers that influence shifting customer and patient behaviors to ensure successful asset launches. Strong track record in collaborating and partnering with cross-unit, cross-functional & key markets to achieve strategic and performance targets. Leadership Capabilities: Proven ability to manage and drive performance, ensuring targets are met and exceeded in challenging markets. Demonstrated ability to lead and inspire teams, drive cross-functional collaboration, and think strategically in dynamic environments. Focuses on larger, longer-term issues, and creates plans and strategies. Comfortable in navigating the matrix and people related organizational dynamics. Establish credibility & influence across diverse stakeholders and able to navigate in an environment of shared outcomes and cross-business accountabilities. Demonstrates enterprise leadership, balance diverse stakeholders and conflicting priorities to drive results. Empowered teams to execute efficiently, through the layers of organization and across geographies. Clearly and effectively communicates with senior stakeholders (both internal &external)- to align on vision, purpose & goals. Generates trust, builds credibility and drives engagement with people and stakeholders. Location: This role is based in Basel, Switzerland Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division International Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Commercial & General Management Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Lead Central Monitor supports the Central Monitoring Head to drive excellence in clinical trial monitoring by establishing and delivering a state-of-the-art Central Monitoring (CM) capability at Novartis in Global Clinical Operations (GCO). The Lead CM is responsible for managing a team of Central Monitors, for developing central and site monitoring strategies, ensuring that the configuration of the CM platform aligns with strategic needs, is consistent with identified indications, program, and study risks, in alignment with the IQRMP, to ensure appropriate trial data surveillance in order to deliver quality and integrity of the trials’ clinical data Apply today and we can thrive together! This role will be based in Basel, Switzerland, Dublin, Ireland or London, UK in a hybrid working approach. About the Role Major accountabilities but not limited to: Support the establishment and implementation of a CM function at Novartis, including processes, tools, and governance frameworks to support RBQM. Manage and mentor a team of CMs, fostering professional development, ensuring alignment with CM processes, and maintaining high performance across the team. Partner with the CM Head to set, refine and implement the CM strategy, contributing to the continuous improvement of Risk-Based Monitoring (RBM) processes across the organization. Oversee the analysis and interpretation of CM dashboards and data visualization tools to identify and contextualize risk signals and ensure accurate root cause analysis and mitigation actions Provide strategic input during protocol development and study setup to ensure comprehensive risk identification and alignment with RBQM objectives and processes. Ensure appropriate trial data surveillance to deliver quality and integrity of the trials’ clinical dat Act as a key stakeholder in the evaluation, adoption, and improvements of the CM tools and technologies, ensuring effective integration into workflows. Drive innovation in the use of analytics, visualization, and data-driven techniques to enhance risk identification and monitoring capabilities. Education & Experience: University degree in life science, business or operations; Advance degree preferred ≥ 7 years of recent pharmaceutical industry experience, with previous experience in clinical research, in a Pharmaceutical Industry or CROs. Strong clinical experience with excellent understanding of clinical trial development and risk management processes and the management of clinical trials (including trial design, protocol development, study start-up, patient recruitment and study close-out). Specific Central monitoring / monitoring experience (hands-on experience with Key Risk Indicators -KRIs- review, centralized monitoring and quality tolerance limits -QTLs-) are strongly preferred, Experience in implementing or working within Risk-Based Quality Management (RBQM) and adaptive monitoring frameworks ≥ 3 years of recent experience in people management and/or team leadership. Strong leadership and people management skills in global setting and proven ability to develop high performing teams and diverse profiles including manager of manager experience. ≥ 5 years comprehensive experience in monitoring (central, site), clinical data analytics, data management activities or equivalent. Knowledge of overall clinical trial ‘planning and execution process, understanding of the protocol, study associated risks and their significance, and the risk management process. Proven experience in developing, implementing, and maintaining quality control documentation for remote/central monitoring activities, ensuring data integrity, completeness, and accuracy. Thorough understanding of the international aspects of drug development process, including expert knowledge of international standards (GCP/ICH), health authorities, and Novartis standards. Advanced critical thinking and analytical skills to understand/analyze/interpret complex clinical and operational data and provide insight into risk signaling, trends, and outliers in data Ability to interpret study protocols, assess study-associated risks, and understand operational and quality implication. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Regulatory Diagnostics Manager (RDM) for Precision Diagnostics is responsible for implementation of strategic plans for development of diagnostics, including companion diagnostics, as they pertain to the Novartis innovative medicines portfolio, including its marketed products. The RDM works with oversight of senior members of the RA Precision Diagnostics Team including the TA and Diagnostics Lead on strategies and submissions including companion diagnostics, in close collaboration with internal RA Disease Unit associates, associates of Digital, Data and Clinical Innovation (DDCI) at Novartis as well as Partner Companies that develop diagnostics and ensures adherence to regulatory requirements. The RDM will also provide regulatory support including tactical and technical regulatory direction for clinical trial assays to ensure compliance with regulations on diagnostics. About the Role Major Accountabilities Regulatory Strategy and Implementation • Supports the diagnostics regulatory strategy for precision IVDs and CDx (e.g. US, EU, Japan, China). • With support of the RA TA and Diagnostics Lead, responsible for submissions in the premarket as well as post-market space including investigational Device Exemptions (IDE), Significant Risk Determinations, Performance Study Applications (PsA) and pre-market authorization submissions • With oversight of the RA TA and Diagnostics Lead, works to ensure diagnostic regulatory input for early development and late- stage programs is incorporated into the overall drug development strategy to ensure regulatory requirements pertaining to IVD, CDx and LDT regulations are met • As needed, partner with RA country organizations to align on local regulatory requirements for precision IVDs and CDx and deliver timely submissions as appropriate including annual reports and notifications • Facilitates preparation, filing, finalization of briefing books including coordination and planning for pre-Submission or other meetings with HAs related to precision diagnostics and CDx development. Participation in HA meetings as appropriate • Develops, manages, and implements plans for timely response to HA requests and coordinates of any applicable follow-up activities. • Member of RA subteam and Biomarker Development Subteam (BDST) as appropriate Training and Compliance Support compliance activities for Novartis clinical trials as they relate to global regulations on precision diagnostics and CDx, such as European IVDR Help ensure regulatory compliance of Partner companies for CDx development and IVD deliverables related to our portfolio, as appropriate and elevate to RA Diagnostic Lead where appropriate Support roll-out of new procedures, SOPs and working practices and training related to IVD and CDx development. Performance Indicators Successful implementation of regulatory diagnostics strategies with timely submissions for precision IVDs and CDx Full compliance with IVD and LDT rules for our clinical trials Identification of precision IVD and CDx needs for Novartis programs Strong partnership with RA Diagnostics Team members and the RA community Adherence to Novartis Policies and guidelines. Experiences & Skills Minimum 2-4 years of experience in the pharmaceutical industry with relevant experience related to diagnostics, IVD or CDx development Science based BS or MS with requisite experience and demonstrated capability. Advanced degree (MS, Ph D, PharmD) considered a plus. Demonstrated experience of successful contributions to a IVD/CDx regulatory project(s) and/or submission Experience in the diagnostic, IVD and/or CDx industry Understanding of IDE, MAA, NDA/BLA, 510(k), PMA submission(s) Understanding of assay validation and CLIA Understanding of clinical trials Strong interpersonal, communication and negotiation skills Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? : https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10046818 Apr 14, 2025 Switzerland Summary The Regulatory Diagnostics Manager (RDM) for Precision Diagnostics is responsible for implementation of strategic plans for development of diagnostics, including companion diagnostics, as they pertain to the Novartis innovative medicines portfolio, including its marketed products. The RDM works with oversight of senior members of the RA Precision Diagnostics Team including the TA and Diagnostics Lead on strategies and submissions including companion diagnostics, in close collaboration with internal RA Disease Unit associates, associates of Digital, Data and Clinical Innovation (DDCI) at Novartis as well as Partner Companies that develop diagnostics and ensures adherence to regulatory requirements. The RDM will also provide regulatory support including tactical and technical regulatory direction for clinical trial assays to ensure compliance with regulations on diagnostics. About the Role Major Accountabilities Regulatory Strategy and Implementation - Supports the diagnostics regulatory strategy for precision IVDs and CDx (e.g. US, EU, Japan, China). - With support of the RA TA and Diagnostics Lead, responsible for submissions in the premarket as well as post-market space including investigational Device Exemptions (IDE), Significant Risk Determinations, Performance Study Applications (PsA) and pre-market authorization submissions - With oversight of the RA TA and Diagnostics Lead, works to ensure diagnostic regulatory input for early development and late- stage programs is incorporated into the overall drug development strategy to ensure regulatory requirements pertaining to IVD, CDx and LDT regulations are met - As needed, partner with RA country organizations to align on local regulatory requirements for precision IVDs and CDx and deliver timely submissions as appropriate including annual reports and notifications Facilitates preparation, filing, finalization of briefing books including coordination and planning for pre-Submission or other meetings with HAs related to precision diagnostics and CDx development. Participation in HA meetings as appropriate - Develops, manages, and implements plans for timely response to HA requests and coordinates of any applicable follow-up activities. - Member of RA subteam and Biomarker Development Subteam (BDST) as appropriate Training and Compliance Support compliance activities for Novartis clinical trials as they relate to global regulations on precision diagnostics and CDx, such as European IVDR Help ensure regulatory compliance of Partner companies for CDx development and IVD deliverables related to our portfolio, as appropriate and elevate to RA Diagnostic Lead where appropriate Support roll-out of new procedures, SOPs and working practices and training related to IVD and CDx development. Performance Indicators Successful implementation of regulatory diagnostics strategies with timely submissions for precision IVDs and CDx Full compliance with IVD and LDT rules for our clinical trials Identification of precision IVD and CDx needs for Novartis programs Strong partnership with RA Diagnostics Team members and the RA community Adherence to Novartis Policies and guidelines. Experiences & Skills Minimum 2-4 years of experience in the pharmaceutical industry with relevant experience related to diagnostics, IVD or CDx development Science based BS or MS with requisite experience and demonstrated capability. Advanced degree (MS, Ph D, PharmD) considered a plus. Demonstrated experience of successful contributions to a IVD/CDx regulatory project(s) and/or submission Experience in the diagnostic, IVD and/or CDx industry Understanding of IDE, MAA, NDA/BLA, 510(k), PMA submission(s) Understanding of assay validation and CLIA Understanding of clinical trials Strong interpersonal, communication and negotiation skills Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? : https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team-s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10041855 Mar 28, 2025 Switzerland Summary We-re a dedicated team united by a drive to deliver significant value to Novartis. You will plan, execute and deliver high quality audits that meet Novartis Internal Audit (IA) methodology standards, strategies and directives. To lead audit teams in activities including assessment of business/information technology risks and evaluation of related internal controls. About the Role Key Responsibilities: Conduct Audits : Lead and perform detailed audits of pharmaceutical supply chain processes, including procurement, manufacturing, distribution, and inventory management. Establish and maintain strong relationship with Novartis internal stakeholders, in particular build strong collaboration to work effectively and seamlessly across our businesses. Risk Assessment : Identify, assess and review potential risks within the supply chain and associated mitigation strategies. Regulatory Compliance : a working knowledge of relevant manufacturing operations regulations, including FDA, EMA, and other global pharmaceutical standards. Process Improvement : Evaluate current processes and recommend improvements to enhance efficiency, reduce costs, and maintain high-quality standards. Reporting : Prepare comprehensive audit reports, summarizing findings, recommendations, and corrective actions for senior management and stakeholders. Data Analysis : As part of the audit or advisory, utilize advanced data analytics and AI where appropriate to identify trends, anomalies, and areas for improvement within the supply chain. Collaboration : Work closely with cross-functional teams, including procurement, logistics, quality assurance, and regulatory affairs, in the understanding and execution of audits and advisories. What you'll bring to the role: Essential Criteria: Degree in a technical or scientific area that contains manufacturing and/or supply chain management, logistics and/or planning. Work experience in technical operations manufacturing and/or supply chain management, planning, logistics and inventory management. Knowledge of pharmaceutical regulations and standards including GMP, GDP and other guidelines. Experience and ability to act in a complex and rapidly changing business environment. Knowledge of process management and/or business process optimization. Fluent in spoken and written English. Willingness to travel (up to 15%) Desirable Criteria: Additional Certifications: Additional relevant certifications such as Certified Supply Chain Professional (CSCP) or Certified in Production and Inventory Management (CPIM), relevant risk management ISO standards, including continuity management experience. Experience with SAP environments. Global Experience: Experience with end-to-end global pharmaceutical supply chains and familiarity with international regulations. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Corporate Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area Audit & Finance Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: JAPAT offices, Switzerland About the role: Would you like to be our Customer Service Support Specialist? At our company will be pivotal in providing high-quality service and hospitality to our notable clientele. This role requires the individual to uphold the company’s high service standards and to anticipate unique client needs. The ideal candidate will play an integral role in enhancing our client’s customer experience. If you're driven by a passion for customer service and aspire to make a meaningful impact, we invite you to join us. This role will require an individual comfortable with flexible work hours as part of a 50% work schedule and should ideally live within a 30-minute radius of Basel airport to accommodate early morning and/or late evening and weekend assignments when necessary. About the Role Key Responsibilities: Provide exceptional customer service to our VIP customers, corporate management, and board members, Utilize strong problem-solving skills to work calmly and efficiently under pressure, responding readily to any ad-hoc requirements or queries. Demonstrate high emotional intelligence and empathy to anticipate and meet the needs of distinguished clients. Showcase detail orientation and maintain the highest standards in service and presentation, providing a clean and pristine environment. Display organizational skills to smoothly coordinate all procedures and schedules while managing time effectively. Engage productively with all departments, assisting with general support activities and ensuring seamless cross-departmental collaboration. Show discretion and trustworthiness, exhibiting a positive and friendly demeanor. Essential Requirements: Several years' experience in high-level customer service, ideally in aviation, luxury hospitality/concierge services, executive assistant roles or as a Corporate Flight Attendant. Excellent communication skills in German and English; knowledge of French would be advantageous. Familiarity with Novartis is a plus Experience with VIP clients and high-ranking business individuals. Able to display excellent host qualities and a warm, inviting demeanor to team members and passengers alike. Displays exceptional detail-orientation and a commitment to maintaining the highest standards in service and presentation. Comfortable with flexible work hours as part of a 50% work schedule and should ideally live within a 30-minute radius of Basel airport to accommodate early morning and/or late evening and weekend assignments when necessary. Languages: Fluent in English and German, French preferred. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a team of dedicated and smart people united by a drive to achieve together. You will proactively identify and analyse key policy trends across Region Europe, collaborating closely with internal and external stakeholders, and shaping policy positions in alignment with expert colleagues. You will ensure the availability of data-driven, predictive analysis informing policy discussions and shaping policy strategy at regional level. This role will also develop and disseminating key policy messages to empower our public affairs teams in Brussels and in national capitals. About the Role Key Responsibilities Identify key policy themes and trendsfor Region Europe by monitoring key policy bodies and legislative processes relevant for the region, in collaboration with the EU Public Affairs team in Brussels Identify policy priorities and significant policy uncertainties for Novartis in Europe and assess their likelihood and impact Digest information and coordinate dissemination of insights across Corporate Affairs and Novartis, ensuring relevant stakeholders are informed and aligned with emerging policy trends in Europe Shape policy strategies, develop policy positions in alignment with internal experts, and articulate clear policy asks Collaborate closely with the Emerging Policies function in the Global Policy team to pull policy intelligence and functional expertise in emerging topics e.g. health data and AI, green tech and license to operate, competitiveness Conduct structured & predictive policy horizon scanning to anticipate future developments in emerging policy areas in Europewith impactful implications for NVS Identify relevant information and actionable policyinsights for Europe from primary and secondary data sources, including internal reports, external research, and open-source intelligence Maintainstrong external network of policy stakeholders in alignment with EU Public Affairs team in Brusselsand attend region-specific external fora, conferences and meetings on policy topics Maintain strong internal network to stay informed on enterprise priorities, key functional priorities and policy needs of keycountries in the region What you'll bring to the role: Essential Requirements: Extensive experience in the pharmaceutical industry, ideally in policy, public affairs, strategy roles within a European context and/or in management consulting Strong knowledge of EU institutions, European policy-making and political dynamics in Europe Experience in identifying key policy uncertainties and develop predictive scenarios that inform decision-making and risk mitigation strategies Experience in crafting policy positions and senior management briefings Ability for forward-looking and predictive monitoring of EU policy landscape, and experience in data-driven scenario planning to anticipate future policy developments and their potential impact on the organisation Desirable Requirements Master's degree (e.g. MSc) / University Diploma or equivalent in relevant discipline. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a core member of the Clinical Trial Team (CTT) independently managing all vendor-related aspects of global clinical trial(s) to deliver study outcomes within schedule, budget, quality/compliance and performance standards, you’ll be accountable for vendor service delivery at study level and collaborate closely with the Vendor Start-up Manager (VSM) for selected services (central labs, electronic clinical outcomes assessment/electronic patient reported outcomes (eCOA/ePRO), interactive response technology (IRT), cardiac and respiratory diagnostics, patient recruitment and retention (PR&R), and imaging reading) during study start-up and leverage your technical and study start-up (SSU) expertise to ensure a timely study start-up. About the Role Key responsibilities: Close interaction and collaboration with study team lead and study team members during study lifetime Review of vendor related protocol sections during protocol development Collaborate with Vendor Start Up Manager to the development of Study Specification Worksheet (SSW) to facilitate bid process. If no VSM is assigned to the category, drive the SSW completion. Manages interface with vendors in cooperation with vendor partner functions Quote/proposal review in collaboration with procurement, support contract negotiations and contributes= to the development of vendor contract amendments Accountable for vendor cost control and vendor service excellence Initiates/co-ordinates vendor kick-off meeting for categories not covered by VSMs Attends vendor kick-off meeting for VSM supported categories Essential requirements: Timely, efficient, and quality execution of assigned trials and trial-related activities within budget, and in compliance with quality standards. Vendor service excellence at study level Proactive operational planning with effective contingency and risk mitigation plans Vendor KPI and KQI dashboards Site readiness monitoring Timely completion of UAT for eCOA and IRT Vendor cost control Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a Clinical Development Medical Director, you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. The Clinical Development Medical Director (CDMD) is the clinical leader of defined program level activities (e.g., submission activities, briefing books, clinical study reports, etc.) and/or a large, complex trial, under the leadership of the Global Program Clinical Head (GPCH). May also lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase). About the Role Major accountabilities: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the clinical development plan (CDP), data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., investigator brochures, briefing books, safety updates, submission dossiers, and responses to health authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors, and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert (CSE). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team, and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Clinical Development Head by providing medical input into CDP and clinical trial package reviews and contributing/driving development of disease clinical standards for disease areas Provide support to the GPCH or CDH in interactions with external partners (e.g., regulatory authorities, key opinion leaders, data monitoring boards, advisory boards, patient advocacy groups), internal partners (e.g., clinical trial team, Medical Affairs, Commercial, Health Economics & Outcomes Research), and decision boards) Work with BR (Novartis Biomedical Research)/Translational Medicine) to drive transition of early development projects to Transition Decision Point and with Business Development, including target identification and due diligences Ensure career development of Program Reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for Global Clinical team Minimum Requirements: MD (or equivalent medical degree) required. Training in cardiology preferred Medical Board certification preferred. 4+ years Clinical practice experience (including residency) preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) required 5+ years of experience in clinical research or drug development from the pharmaceutical/biotechnology industry, preferably spanning clinical activities in phases I through IV 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrixed environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of Good Clinical Practice, clinical trial design, statistical analysis methodology, and regulatory/clinical development processes People management experience preferred, especially at the global level (this may include management in a matrixed environment) Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The International MA team represents the voice of the International markets, with a focus on our top priority markets and addresses their needs across pre-launch, launch, life-cycle management and in-market. Responsible of key strategic areas within the International TA and deputize the Head of International Medical Affairs CRM in key leadership forums. Provides aligned input from the top priority International markets into IEP and is responsible for the implementation of the scientific communications and medical education strategy, as well as relevant medical standards in these markets. Supports the planning and execution at International for the medical/scientific engagement strategy (MSL / Field Medical Affairs strategy, medical education programs, scientific publication planning and Medical Expert network development) addressing and delivering strategic pre-launch and launch medical activities needs for patient, clinical, access and value to health care systems. Acts as a subject matter expert in the development of the overarching strategies for International, providing inputs during design and along the end-to-end execution of programs. Provides leadership and deep medical expertise across TAs, pivoting support based on business priorities. Acts a strategic partner to International Commercial, International Value & Access, Global, Regional and US MA, and Development. About the Role Key responsibilities: Lead the International Medical Affairs team for a particular disease area (Renal) including managing international medical directors (direct reports) and any medical directors on temporary rotation/assignment to the team. Oversee the medical affairs launch strategy for all priority programs in key International countries including transformational tactics such as: research/population health, innovative partnerships and integrated evidence plans. Partner with Medical Affairs organizations in key countries to ensure strong delivery focused on country needs. Advisor to plans for evidence generation, MSL / Field Medical Affairs strategy, medical education programs, scientific publication planning and Medical Expert network development with TAs. Co-own the development and implementation of innovative education and scientific communication plans for all brands for external stakeholders at International. Financial tracking to ensure timely and cost-effective development & execution of medical activities. Partner with Development, Global Medical Affairs (GMA), International Value & Access & International Commercial and Launch Strategy (CLS) to shape launch portfolio and diversify evidence to achieve broad access at launch and to enhance impact on clinical practice for priority programs. Represent International Medical Affairs around prioritized portfolio with internal (GMA, Development, Biomedical Research etc.) and external audiences, in collaboration with CLS including the investment, medical and regulatory communities, as well as pharmaceutical or biotechnology industry collaborators/partners. Represent “the voice of the patient” internally and evaluate factors relevant to a patient’s informed decision making. Ensure that Patient Access programs are supported for all brands within International Medical Affairs and delivered with full compliance. Provide direction and input into the development and implementation of successful reimbursement and market-access strategies. Provide input to shape Field Medical Strategies, develops, and executes Field Medical plans, ensure implementation of key Field Medical initiatives, e.g., insight gathering, sharing and translation into action, development and conduct of trainings on disease area and medical/ scientific knowledge, and guides MSL resourcing and deployment.Provide proactive medical input to asset lifecycle management to consider new therapeutic opportunities. Ensures International Medical Affairs activities are designed and executed in compliance with company policy guidelines and highest medical quality standards. Essential requirements: MD (Preferred) or PhD/PharmD in Health Sciences. Specialist Degree or specialist qualification related to discipline for which is responsible is an advantage 7+ years in Pharmaceutical Industry experience in Medical Affairs and/or Clinical Development Strategic mindset and able to establish credibility and influence across a range of diverse stakeholders in a matrix organization to drive change Deep understanding of health care systems and key external stakeholders. Agile mindset & ability to lead in an agile organization across Disease Areas Understands unmet medical needs, generates the right evidence to fulfil them, uses innovative, multichannel communication formats for effective evidence dissemination Ability to truly collaborate across functions and markets: serve-partner-co-create. Credibility as peer expert with external stakeholders Able to navigate in an environment of shared outcomes and cross-business accountabilities. Critical thinker and with ability to navigate uncertainty without major supervision. Strong track record of delivery focus for time and quality in medical affairs projects. Successful development and implementation of innovative programs and processes Desirable requirements: Highly preferred: Significant medical affairs pre-launch and launch experience in major markets (ie Germany, China, Japan). Experience in renal disease. Experience in developing and executing “Best in Class” processes at scale Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland; East Hanover, USA - #LI-Hybrid To apply to this role in the US please go to REQ-10046334 Executive Director, Integrated Insights About the role: We are excited to invite you to join us as our Executive Director of Integrated Insights. Imagine leading a global role where you spearhead a predictive analytics and insights team within Corporate Affairs. You will empower Communications, Government Affairs, ESG, and Global Health teams with critical data and intelligence, enabling them to craft strategic plans, boost performance, and strengthen stakeholder engagement. This position offers you the opportunity to oversee market research, performance measurement, and stakeholder mapping, ensuring that Corporate Affairs initiatives align seamlessly with business goals. Plus, you'll lead a dynamic team of 3 passionate members who are ready to innovate and excel under your guidance. Are you ready to make a significant impact? About the Role Key Responsibilities: Develop and execute a comprehensive analytics and insights strategy aligned with Corporate Affairs teams and objectives, leveraging advanced data analytics techniques to proactively identify market opportunities and risks. Lead the implementation of predictive analytics models to forecast market dynamics, anticipate shifts in stakeholder behavior, and inform strategic decision-making across the function. Lead the functions adoption of AI-driven strategic approaches and tools/platforms to capture efficiencies and increasingly power teams and projects with proven AI methodologies and a true data-science approach. Collaborate cross-functionally to integrate insights, optimize engagement strategies, and enhance resource allocation based on data-driven recommendations. Drive the development and enhancement of data infrastructure and analytics capabilities to ensure the timely delivery of actionable insights and the continuous improvement of analytical methodologies. Establish and track key performance indicators (KPIs) and metrics to measure the effectiveness of functional performance and analytics initiatives, report progress against strategic goals, and communicate insights to executive leadership. Champion a data-driven culture within the organization by promoting the importance of evidence-based decision-making, providing training and support on data analytics tools and methodologies, and fostering a collaborative environment for knowledge sharing. Stay abreast of industry trends, emerging technologies, and best practices in analytics and insights, and assess their potential impact on the company's competitive positioning and strategic priorities. Cultivate relationships with and manage a diverse range of external partners, including agencies and vendors, to access additional expertise, data sources, and analytical capabilities that can further enhance the company's analytics and insights capabilities. Essential Requirements: Bachelors Degree. Extensive years of experience in a data and insights role in the communications or government affairs area. Effectiveness of insights in informing strategies and tactics, changing practice, and enabling the entire Corporate Affairs function—from communications and government affairs to our ESG team and beyond. Timely and comprehensive reporting of performance on functional and project objectives to senior leadership. Proactive and efficient management of processes, ensuring timeliness and high-quality execution. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10046338 Apr 09, 2025 Switzerland Summary Location: Basel, Switzerland; East Hanover, USA - #LI-Hybrid To apply to this role in the US please go to REQ-10046334 Executive Director, Integrated Insights About the role: We are excited to invite you to join us as our Executive Director of Integrated Insights. Imagine leading a global role where you spearhead a predictive analytics and insights team within Corporate Affairs. You will empower Communications, Government Affairs, ESG, and Global Health teams with critical data and intelligence, enabling them to craft strategic plans, boost performance, and strengthen stakeholder engagement. This position offers you the opportunity to oversee market research, performance measurement, and stakeholder mapping, ensuring that Corporate Affairs initiatives align seamlessly with business goals. Plus, you'll lead a dynamic team of 3 passionate members who are ready to innovate and excel under your guidance. Are you ready to make a significant impact? About the Role Key Responsibilities: Develop and execute a comprehensive analytics and insights strategy aligned with Corporate Affairs teams and objectives, leveraging advanced data analytics techniques to proactively identify market opportunities and risks. Lead the implementation of predictive analytics models to forecast market dynamics, anticipate shifts in stakeholder behavior, and inform strategic decision-making across the function. Lead the functions adoption of AI-driven strategic approaches and tools/platforms to capture efficiencies and increasingly power teams and projects with proven AI methodologies and a true data-science approach. Collaborate cross-functionally to integrate insights, optimize engagement strategies, and enhance resource allocation based on data-driven recommendations. Drive the development and enhancement of data infrastructure and analytics capabilities to ensure the timely delivery of actionable insights and the continuous improvement of analytical methodologies. Establish and track key performance indicators (KPIs) and metrics to measure the effectiveness of functional performance and analytics initiatives, report progress against strategic goals, and communicate insights to executive leadership. Champion a data-driven culture within the organization by promoting the importance of evidence-based decision-making, providing training and support on data analytics tools and methodologies, and fostering a collaborative environment for knowledge sharing. Stay abreast of industry trends, emerging technologies, and best practices in analytics and insights, and assess their potential impact on the company's competitive positioning and strategic priorities. Cultivate relationships with and manage a diverse range of external partners, including agencies and vendors, to access additional expertise, data sources, and analytical capabilities that can further enhance the company's analytics and insights capabilities. Essential Requirements: Bachelors Degree. Extensive years of experience in a data and insights role in the communications or government affairs area. Effectiveness of insights in informing strategies and tactics, changing practice, and enabling the entire Corporate Affairs function-from communications and government affairs to our ESG team and beyond. Timely and comprehensive reporting of performance on functional and project objectives to senior leadership. Proactive and efficient management of processes, ensuring timeliness and high-quality execution. Benefits and rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Corporate Affairs Business Unit CTS Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 East Hanover, New Jersey, USA Functional Area Communications & Public Affairs Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Clinical Science Risk and Change Management Associate Director is responsible to drive proactive risk management in Translational Clinical Oncology (TCO) to maximize the impact of remediation and mitigation plans and prevent occurrence of issues. This role also ensures that changes are implemented smoothly and efficiently, leading to improved organizational performance. This includes better alignment of resources, streamlined processes, and enhanced productivity. About the Role Key Responsibilities: Support Risk Based Quality Management (RBQM) by monitoring risk registered data in collaboration with Process Compliance Managers (PCM) to understand team behaviors towards risk management and issue documentation. Influence TCO teams to achieve proactive remediation and mitigation of risks and minimize occurrence of issues. Work with Risk Management and risk registered subject matter experts (SMEs) on all matters pertaining to trial risk management. Ensure communication and training of Clinical Trial Teams (CTT) on risk-related processes. Collaborate with the Risk Surveillance Lead community in Development, sharing TCO feedback and optimizing ways of working, to achieve a mutual understanding of risk management in TCO trials and alignment of risk management approach across TCO trials. Liaise with Vendor Program Strategy Director (VPSD) function to align on vendor risks/issues, based on feedback collected from TCO trial teams. Communicate relevant vendor risk/issue related information to TCO trial teams. Serve as the Point of Contact for the global Business Disruption Committee, providing the TCO perspective, supporting risk assessments, and coordinating with teams on relevant risks/issues and related action items. Coordinate the TCO business disruption taskforce, as needed. Contribute to global and TCO specific work streams and initiatives, in collaboration with Operations Excellence, by supporting with risk assessment, mitigation plans, and change management. Assess changes in the broader organization that may potentially impact TCO. Set-up and implement relevant change management plans as applicable for TCO. Engage with relevant stakeholders within and outside TCO to build trust and ensure alignment. Ensure clear communication about changes, its benefits and risks, as applicable. Provide clear communication and maintains effective collaboration with TCO teams to enhance their understanding of change and how it benefits them and the organization, thereby reducing resistance and increasing acceptance. Assure sustainability of changes with continuous monitoring, feedback loops, and adjustments to ensure that the change remains effective and delivers the desired outcomes. May contribute as subject matter expert for risk-related Standard Operating Procedures (SOP)/Working Practices (WP) and others as applicable. Essential Requirements: B.S. or advanced degree preferably in life sciences/healthcare or equivalent experience. A minimum 8 years of relevant experience in the Pharmaceutical or Biotech industry with experience in trial management, risk management and/or change management. Demonstrated ability for leading initiatives with cross-functional teams and implementation of recommendations. Developed or have participated in the development of guidance documents, trainings, SOPs, work practices and tracking tools. Experience working in matrix environment and in global teams. Excellent interpersonal, problem-solving, negotiation and conflict resolution skills. Excellent organizational, communication and presentation skills (oral and written). Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? : https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated, passionate scientist and leader specialized in RNAi therapeutics to join the xRNA group within Biologics Research Center (BRC) in Basel, Switzerland as Principal Scientist, xRNA. The xRNA team strives for excellence and drives a diverse portfolio of siRNA assets and platform innovation to attenuate gene expression via RNAi. Our xRNA team is dedicated to excellence, constantly pushing for novel advancements in our diverse portfolio of siRNA assets and platform strategies to modulate gene expression through RNAi. The team's collaborative efforts with Disease Area groups, Global Discovery Chemistry, and Discovery Sciences are focused on expanding the application of RNAi beyond the liver. About the Role As Principal Scientist in xRNA Therapeutics, you will have an opportunity to join the Biologics Research Center (BRC) as a leader at the cutting edge of innovative medicine development to improve patient lives. BRC builds the biologics pipeline in collaboration with Biomedical Research Disease Areas via a breadth of technologies for discovery of antibody, protein, gene therapy and RNA-based therapeutics. The successful candidate will have a strong research track record in drug discovery and will provide key expertise in the development of next generation RNA based medicines and their acceleration to patients. They will lead boldly and collaborate effectively across therapeutic and functional areas to advance our growing RNA portfolio across various diseases states. Key Responsibilities: Lead a team of highly talented scientists on the Basel site responsible to drive RNAi based therapies to patients via design, screening and characterization. Establishes mid- and long-term goals, plan of action and implementation for the local xRNA team in line with global strategy for xRNA and Biologics Research Center Develops and implements strategy for next generation extrahepatic RNAi for various disease areas including renal, cardiometabolic, and cardiovascular. Co-leads RNAi drug discovery and development in partnership in Global Discovery Chemistry and Disease Areas. Collaborate with downstream development colleagues to bring lead candidates towards full development. Collaborates and coordinates activities with other global BRC and functional groups Offers innovative approaches to scientific questions and troubleshooting efforts. Identifies Disease Area’s unmet needs and collaborate for a novel therapeutic solution. Role Requirements: PhD level scientist with 5 years of relevant experience, recognized both internally and externally as an expert in RNAi Prior experience with drug discovery focused on RNAi design, screening, and characterization Deep knowledge of RNAi chemistry and biology applied to lead optimization of therapeutic candidate A proven track record of success as judged by publications and patents Knowledge in the application of RNAi to biology in the areas of renal metabolic diseases is desirable Highly collaborative spirit to accelerate programs to clinic; good communication skills, creativity, and multi-tasking in a fast-paced environment. Excellent, oral and written communication skills Experience with extrahepatic/kidney targeting of RNAi is a preferred *Restrictions on flexible working arrangements may apply and will be discussed at interview if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Job Description Summary The Clinical Development Director (CDD) in the Cardio Renal & Metabolic (CRM) Development Unit is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As a CDD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive the execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: • Providing clinical leadership and strategic input for all clinical deliverables in the assigned project or section of a clinical program. Clinical deliverables may include clinical sections of individual protocols or sub studies consistent with the Integrated Development Plans (IDP), clinical data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications • Leading development of clinical sections of trial and program level regulatory documents • Driving execution of the section of the clinical program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, if applicable • Overseeing/conducting ongoing medical and scientific review of clinical trial data with Clinical Scientific Expert(s) with appropriate oversight from Medical Lead • Supporting (Sr.) GPCH in ensuring overall safety of the molecule for the assigned section and may be a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety • As a clinical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • Contributing to scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training and may be the Program Manager of other associates Minimum Requirements: • Advanced degree in life sciences / healthcare (or clinically relevant degree) is required. PharmD or PhD is strongly preferred*** • Fluent oral and written English • Minimum 7 years experience in clinical research or drug development • Working knowledge of the assigned disease area is desired with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) or program level • Demonstrated ability to establish effective working relationship with key investigators • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Strong communication skills with the ability to work in a cross functional and global organization Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary With over 60 years history in neuroscience, Novartis brought landmark therapies to patients with Multiple Sclerosis, Alzheimer’s disease, Parkinson’s Disease, Epilepsy, Depression and Migraine. We have a world-class pipeline in neuro-inflammation, neurodegeneration, psychiatric and neuromuscular diseases. Our holistic R&D approach includes cutting edge molecules, comprehensive approaches to technology, biomarker and digital therapeutics to propose better solutions for patients worldwide. About the Role As Global Program Clinical Head (GPCH), you are the clinical lead of Neuroscience, full development product. As a key member of the Global Program Team, you will contribute to the overall strategy in collaboration with relevant other functions such as Regulatory Affairs, Market Access and others. You will develop and ensuring the implementation of the Clinical Development plan and leading a cross functional team of specialists such as Medical Directors, Trial Directors, Safety Leaders, Biostatisticians and Regulatory Directors. The GPCH works to ensure early development plans and proof of concept studies are aligned with Development strategy and leads licensing evaluations for Clinical Development for the therapeutic area. In addition, you will lead the development and execution of the disease area strategy. What you’ll be doing: Responsible for clinical input to support Business Development & Licensing (BD&L) activities Serve as the Clinical Development Representative to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) Contribute to Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or more treatment indications and/or multiple programs. Drive creation and implementation of Clinical Development to support decision analysis and optimal resource allocation in program(s). Lead a cross functional team through the creation of clinical components of key documents (e.g., Clinical Trial Protocols, Investigator’s Brochures, Clinical Study Reports, regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency. As the medical expert, lead interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs, Marketing, Health Economics & Outcomes Research), and internal decision boards Together with Patient Safety, ensure continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Support registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Plan and implement publication and clinical communication strategy in coordination with Global Medical Affairs and Medical Writing, and provide input into key external presentations What you’ll bring to the role: MD, or PH. D degree with 10+ years’ experience in clinical research or drug development in an industry environment spanning clinical activities in Phases I-III/IV, including submission dossiers. A passion for Neuroscience Advanced expertise in Neuroscience with ability to innovate in clinical development study designs, provide relevant evidence to decision-makers and to interpret, discuss and present clinical trial or section program level data Detailed knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Desirable: MD or equivalent, MD or MD/PhD in Neurology, Experience in Cell&Gene, Rare or Neuromuscular diseases, Neuroinflammation of interest (preferred). This is a hybrid role and it can be based in Basel, London or Barcelona. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, colour, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Established in 2007, Basel Drug Substance Supply (BDSS) is a Novartis biotech site where about 160 associates produce and test clinical and commercial drug substances and cell banks. BDSS contributes to global Novartis biotech operations by playing a crucial role in launching new biological entities. During your internship in our MS&T (Manufacturing Science and Technology) unit you will be able to work with Validation Experts and Products Stewards to support launches of new products. About the Role Preferred start date: asap Latest start date: flexible Duration: up to 12 months Location: Basel Klybeck; hybrid working possible with 3 days per week on site Key responsibilities: Collecting data for manufacturing process parameter as well as analytical results. Data mining to check for potential performance differences on production lines. Trending the performance of cleaning processes over time and for different products. Determining the capability and stability of production process by statistical analysis of the analytical data. What you’ll bring to the role: Essential requirements: Education: Bachelor/Master student in Biotechnology, Biology, Chemistry or Pharmacy. Languages: Englisch, German (understanding) Desirable requirements: Being curious to learn more about state-of-the-art industrial processes of monoclonal antibodies. Basic understanding of biotech manufacturing processes and statistics. Please submit a cover letter that includes your motivation for the position and from when you will be available. Thank you. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We have an exciting opportunity as a Monitoring Excellence Head. In this role, you will be leading the strategic vision, drive end-to-end functional excellence in clinical trial monitoring, foster collaboration within the organization across global, hubs and country teams with the business across programs and trials for clinical trial teams-roles interacting with monitoring roles (CRAs, Central Monitors, CPMs). Apply today and we can thrive together! This role will be based in Basel, Switzerland, Dublin, Ireland or London, UK in a hybrid working approach. About the Role Major accountabilities but not limited to: Establish and implement a Monitoring Excellence function at Novartis, which includes two organizational pillars: central monitoring and field monitoring excellence and ensure the alignment between two pillars. Establish and actively monitor central monitoring objectives in line with Global Clinical . priorities, key metrics/KPIs and industry benchmarks. Oversees and reports on monitoring performance, challenges, and opportunities for improvement for senior leadership. In the long-term, ensure central monitoring function evolves and adjusts to a remain a value-added function and to ensure compliance with latest regulations. Coordinate cross-functional interactions between monitoring teams and key stakeholders within Development in areas such as Clinical Data Operations (especially with Data Analyst team to support Central Monitoring’s technologies), process and compliance, quality assurance, and regulatory affairs. Serve as the central point of contact for monitoring-related queries for HA sponsor’s inspections and group audits, coordinating preparation activities, providing expert insights, facilitating responses and follow-up actions. Set-up a functional center of excellence in field monitoring in line with best-in-industry practices. Ensure that monitoring organization structure and capabilities are aligned to effectively address current needs (internals/externals). In partnership with Site and Study Operations Hubs and Country Leadership, establish and implement global strategies to increase and sustain high performance and quality in monitoring activities. Develop and implement frameworks for monitoring performance metrics, provide strategic leadership to field monitoring teams, establishing monitoring best practice and standards, ensuring consistency across Hubs and countries. Establish solid collaboration with Clinical Data Operations and Clinical Development functions to consider interdependencies with other key activities relating to Data Quality and RBQM and synergized actions to drive robust operational performance within Development. Guide the organization through the transition to a Central Monitoring model, driving cultural and operational change to achieve buy-in and sustained success. Oversee the deployment of technology for Central Monitoring, in collaboration with Clinical Data Operations. Video Link https://www.youtube.com/watch?v=ggbnzRY9z8w Essential Requirements: University degree in life science, business or operations. An Advanced degree is preferred with 10+ years of recent pharmaceutical industry experience, with previous experience in clinical research, in a Pharmaceutical Industry or CROs. Strong clinical and budgeting/finance experience with excellent understanding of clinical trial development and risk management processes and the management of clinical trials. Specific central monitoring / monitoring experience preferred. 8 years of recent experience in people management and/or team leadership. Strong leadership and people management skills in global setting and proven ability to develop high performing teams and diverse profiles including manager of manager experience. Thorough understanding of the international aspects of drug development process, including expert knowledge of international standards (GCP/ICH), health authorities (FDA/EMEA), local/National Health Authorities regulations and Novartis standards. Strong capability in working in a Global/Country matrixed environment. Organizational awareness, including significant experience working cross-functionally. Proven track record in study operations process set-up and/or improvement(s). Exceptional technical, analytical and quantitative problem-solving skills. Strong strategic thinking and ability to articulate the bigger picture to foster confidence and trust. Experience in building-up a new organization: building a new capability (or transformation significantly an existing capability) with demonstrated adaptability and by embracing change and new approaches. Proven experience in prioritizing transformation, leveraging AI and analytics, and focusing on transformative investments. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary This role will act as liaison between Finance, DDIT, and Digital Finance teams to ensure project and solution alignment & establish governance processes. Responsible for Data Management governance across various tools, systems, and products in Digital Finance. About the Role Your responsibilities include, but not limited to: Act as the primary connection across Finance, DDIT and Digital Finance teams to ensure overall solution and Project delivery alignment. Understanding of data flows in the Business, Planning & Analysis (BPA) world (commercial) Governance of the master data hierarchies across tools/systems/products in Digital Finance Set up process for this governance Liaise with business (Corp, US, International, Regions, Countries) to collect all requests and perform the assessment Governance of actuals and planning versions published in the tools, as well as the calendars Liaise with business (Corporate, US, International, Regions, Countries) to understand the processes and dependencies Might extend to all units for certain reports/processes Performs and maintains confidentiality assessment of data, keeping up with considerations coming from the different units, e.g. the Swiss data restrictions and the impact on the tools / Data confidentiality reassessment triggered by the 141 changes and Sandoz spin-off Generates and maintains the guidelines for user access, establishing with the units which users should have access to which data, and harmonizing across D&T Is in contact with the EDO office, ensuring Digital Finance complies with the Finance EDO and EDM guidelines Understands data sources (FRA, LDC, etc.) and can establish links with both teams to anticipate changes that may impact data security, master data or governance What you'll bring to the role: Relevant degree (e.g.: Business, Finance), or demonstrated comparable experience in business, management or engineering. Proficiency in English required – spoken & written, other languages is an asset. Demonstrated Project Management experience – certification in project management is desirable. Very strong process orientation. Experienced in Data management using industry standard tool. Technical orientation, good understanding of data bases and systems (preferably for Finance Data Reporting & Analytics). Proven experience working with technical teams/developments. Good problem solving, hands-on and analytical - a strong team player with solution orientated and initiative-taking mindset. Experience working in multi-functional settings, across multiple organizational level Ability to deal with highly complex environment, translating complexity into actionable recommendations Good analytical skills linked with conceptual thinking capabilities Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland; The role will act as liaison between Finance, DDIT, and Digital Finance teams, leading projects on key finance processes for global & headquarter core applications that support Novartis financial planning & reporting. About the Role Your responsibilities include, but not limited to: Act as the primary connection across Finance, DDIT and Digital Finance teams to ensure objectives alignment Own and drive the end-to-end delivery. This includes planning, executing and closing the project, including establishing the operational setup (process and technical) with minimal guidance Identify and qualify new demand with overall responsibility for steering proposals through the early phases of approval Understand the processes, plans, objectives, drivers, and issues related to the business capability, as well as the appropriate “non-core” policies and regulations, such as data management policies Understand the project requirements and involve the right cross-functional team members at the right time Significantly contribute and drive multi-year, large-scale project roadmaps for key finance processes on global & headquarter core applications with significant impact on Novartis financial results Ensure digital technology impact analysis is provided to business Communicate complex results into simple conclusions that will empower leadership to drive action based on the insights you derive Effectively engage with business stakeholders and translate business requirements into detailed project requirements. Define business acceptance criteria and test functionalities of developed features to ensure they meet business needs. Foster best-in-class reporting and analytics solutions by understanding and anticipating business needs and user experience (UX). What you'll bring to the role: Relevant degree (e.g. Business, Finance), or demonstrated comparable experience in business, management or engineering. Proficiency in English required – spoken & written, other languages is an asset. Ability to effectively engage with business stakeholders and translate business requirements into detailed requirements which can be taken further for system implementations. Demonstrated Project Management experience – certification in project management is desirable. Strong process orientation. Proven project/product management experience, including planning, executing and closing projects, as well as managing teams and resources. Experience in driving change of business processes based on technological solutions Strong stakeholder management Excellent organizational skills to manage multiple tasks and projects simultaneously Ability to identify potential risks and develop mitigation strategies, reprioritizing if necessary Experience working in multi-functional settings, across multiple organizational level Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a member of the RA Data & Technology global leadership team, the Data Strategy and Management Platform Lead contributes to the strategic vision of Regulatory Affairs by leading a team of associates to support the digitalization and centralization of Data Strategy and Management in RA, by overseeing capabilities for Data Standardization and Quality; Business Architecture and Data Integrations; and Analytics, Dashboards, & Reporting which are underlying the Platform. The Data Strategy and Management Platform Lead is responsible for setting the overall platform strategic direction, establishing and enforcing data governance across all functions to drive harmonization and continuous improvements to the data landscape on data quality and maturity as well as emerging requirements, setting platform priorities in preparation for budget review and ensuring that projects and activities are completed in line with allocated budget to maximize business benefits. About the Role Major accountabilities: Team Leadership:Lead a diverse global team to ensure alignment with organizational goals and business priorities related to Data Strategy and ManagementDefine and communicate the strategic vision for Data Strategy and Management capabilities, fostering a culture of excellence and continuous improvement.Regularly assess team performance against established metrics and objectives. Provide feedback, recognize achievements, and address areas for improvement through coaching and development opportunities.Promote a collaborative and inclusive work environment, where team members are empowered to contribute to their full potential. Roadmap Development:Accountable for the development of a roadmap for RA Data Strategy and Management, working in close collaboration with RA D&T LT, RA stakeholders, and other line functions as appropriate, in alignment with the Development and enterprise data strategy. Stakeholder Engagement:Ensure continuous expansion of knowledge and foster adoption of a data and digital mindset in Regulatory Affairs, ensuring compliance and proactive readiness of the RA data landscape to regulatory requirementsRepresent the RA department in cross-functional data governance boards and line function management meetingsBuild and maintain collaborative and productive partnerships with stakeholders to achieve business priorities Collaboration and Partnerships:Develop and nurture relationships with other functions and external partners to ensure the expansion of data solutions across the portfolio and alignment to the development and enterprise data strategy and roadmap.Oversee vendors at the Platform level, in collaboration with IT and External Partnership Teams Quality and Compliance:Ensure on-time, compliant, secure, and quality delivery of portfolio for the assigned capabilities, aligned with the NVS Quality Manual.Contribute to the change management strategy to ensure smooth adoption of data initiatives, as requiredEnsure adherence to Security and Compliance policies and procedures within the scope of the Platform, and prepare for audit readiness and inspection requirements (incl. Related mitigations or actions triggered by audits & inspections). Project and Program Support:Provide support and resources for key projects and programs impacting the underlying capabilities to ensure timely delivery of high-quality milestones that align with business requirements. Collaborate with business, IT, and other stakeholders to develop and define project scope, objectives, and interdependencies for projects. Demand Management:Effectively manage demands for data services and operational support arising from various functions within Regulatory Affairs. Ensure monitoring of overall service delivery performance and backlog. Regulatory and Industry Trends:Ensure proactive identification of relevant regulations and guidelines and influence the regulatory data landscape by contributing to interactions with Health Authorities or to relevant external working groups and initiatives (e.g., EFPIA, PhrMA, ICH)Ensure data benchmarking and looking at the industry trends and health authority landscape in order to identify unmet needs and opportunities for investments where digital data solutions can positively impact Regulatory Affairs to increase efficiency, automation and quality of deliverables. Work Experience: 8+ years of relevant industry experience Bachelor’s degree, master’s or commensurate experience; Advanced degree in life science, pharmaceutical, technology or data science preferred. Matrix / cross-functional leadership experience preferred Strong understanding and direct relevant experience with the data Strategy and management landscape of pharmaceutical regulatory affairs and regulatory information management Strong understanding of regulatory requirements and structured data submissions standards and initiatives Strong strategic problem-solving skills and ability to navigate un-charted territory without clear precedent Experience presenting/speaking at a senior management level with a proven track record of effectively communicating complex initiatives Strong global leadership skills demonstrated by a proven track record of successfully managing people, technology initiatives and/or leading groups or teams, inspiring innovative, strategic and big picture thinking. Demonstrated leadership in driving risk assessment and mitigation, clear strategic thinking, prioritization, maintaining awareness of global patient and business impact. Strong negotiation skills Excellent verbal and written communications Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a key member of the RA Data and Technology Function, the Director of Platform Operations will shape and execute the operational strategy, delivering business benefits through harmonization and continuous improvement. Leading a team of associates, this role ensures efficient Platform Operations for RA systems. The Platform Operation oversees Release Management, Migration, Validation and Business Administration capabilities. These respectively support RA technology products by ensuring continuous alignment and deployment of releases; defining strategy and executing migration of data and information; ensuring access control, security management and continuous operation and availability of technology products. The Platform Operation Lead is accountable to ensure that the overall platform strategy delivers business benefits, drives harmonization and continuous improvements. By aligning the digital strategy and initiatives with regulatory priorities, the Platform Operation Lead plays an essential role in enhancing the efficiency, consistency and agility of regulatory activities, strengthening the organization’s ability to respond effectively in a dynamic global landscape. About the Role Major accountabilities: Team Leadership: Lead a diverse global team to ensure alignment with organizational goals and business priorities related to Submissions and Registration Management Define and communicate the strategic vision for Submission and Registration Management capabilities, fostering a culture of excellence and continuous improvement. Regularly assess team performance against established metrics and objectives. Provide feedback, recognize achievements, and address areas for improvement through coaching and development opportunities. Promote a collaborative and inclusive work environment, where team members are empowered to contribute to their full potential. Roadmap Development: Define, prioritize, and deploy an integrated platform roadmap in collaboration with RA D&T LT, relevant stakeholders, and DDIT partners, ensuring alignment with the Development and Enterprise technology strategy roadmaps. Stakeholder engagement: Represent the platform in digital governance boards and leadership meetings across the organization Represent the platform in digital networks, externally (e.g. across Industries) as needed Communicate effectively to ensure understanding and support for new technology initiatives. Support continuous expansion of knowledge and foster the adoption of a digital mindset within Regulatory Affairs. Collaboration and Partnerships: Build and maintain collaborative and productive partnerships across the Platform team and enterprise stakeholders to achieve business priorities. Oversee vendors at the Platform level, in collaboration with IT and External Partnership Teams Quality and Compliance: Ensure on-time, compliant, secure, and quality delivery of portfolio for the assigned capabilities, aligned with the NVS Quality Manual. Contribute to the change management strategy to ensure smooth adoption of technology initiatives, as required Ensure adherence to Security and Compliance policies and procedures within the scope of the Platform, and prepare for audit readiness and inspection requirements (incl. Related mitigations or actions triggered by audits & inspections). Project and Program Support: Provide support and resources for key projects and programs impacting the underlying capabilities to ensure timely delivery of high-quality milestones that align with business requirements. Collaborate with business, IT, and other stakeholders to develop and define project scope, objectives, and interdependencies for projects. Demand Management: Effectively manage demands for technology services and operational support arising from various functions within Regulatory Affairs. Ensure monitoring of overall service delivery performance and backlog. Industry Trends: Stay updated with industry trends and emerging practices to drive agility, speed, efficiency, and effectiveness within the team. Accountable for release management processes to ensure timely and coordinated delivery of software updates and system enhancements across global platforms. Accountable for the establishment of validation frameworks/standards for essential system platforms and applications to ensure compliance with regulatory and industry standards within the life sciences sector. Accountable for the establishment of migration frameworks/standards and the managing/executing of migration projects, ensuring a seamless transition and integration of new Systems, Data and Applications with minimal disruption to business. Accountable for the establishment of Business Administration frameworks/standards and implementation for the management of RA technology programs, focusing on efficiency and effectiveness. Work Experience: 8+ years of industry experience Bachelor’s degree: master’s or commensurate experience. Advanced degree in life science, pharmaceutical, technology, or data science preferred Matrix / cross-functional leadership experience preferred Strong understanding and direct relevant experience with the technology landscape operations of pharmaceutical regulatory affairs Strong strategic problem-solving skills and ability to navigate un-charted territory without clear precedent Experience presenting/speaking at a senior management level with a proven track record of effectively communicating complex initiatives Strong global leadership skills demonstrated by a proven track record of successfully managing people, technology initiatives and/or leading groups or teams, inspiring innovative, strategic and big picture thinking. Demonstrated leadership in driving risk assessment and mitigation, clear strategic thinking, prioritization, maintaining awareness of global patient and business impact. Strong negotiation skills Excellent verbal and written communications Strong experience in technology process requirements, migration, release management, and validation/testing including audit and knowledge of regulatory requirements Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a team of dedicated and smart people united by a drive to achieve together. The Director, Portfolio Advocacy, Public Affairs RE will drive and execute targeted public affairs activities for policy priorities across the Novartis portfolio in Region Europe, focusing on both in-market and launch products in alignment with regional commercial priorities. You will also play a crucial role in collaborating closely with internal stakeholders and aligning policy priorities across Portfolio Policy, Region and Country Public Affairs to shape advocacy activities across the Novartis portfolio in Region Europe. About the Role Key Responsibilities: Drive public affairs activities for policy priorities across the NVS portfolio in Region Europe Focus on regional priorities, for both in-market and upcoming launches, and define clear launch prep timeline based on key market needs Shift priorities fluently in function of enterprise priorities and portfolio policy guidance within the region Connect with Portfolio Advocacy counterparts in the other regions to build strong network and share best practices across regions Build interfaces with commercial counterparts in the international region and with key countries Focus on execution of advocacy plans at country and regional level Represent Novartis in key trade associations at regional level with focus on relevant therapeutic areas or topics, aligned with Portfolio Executive Directors Aligned, measurable joint objectivesetting for the countries for portfoliotopics with Country Public Affairs Heads andRegion Europe Public Affairs cluster leads, connecting the dots between theproduct, country and region lens What you'll bring to the role: Essential Requirements: Proven experience in the pharmaceutical industry, ideally in a policy, advocacy or commercial role Prior work experience at regional level and within a local market organisation Strong understanding of advocacy and engaging external policymakers, skilled in building forward-looking Public Affairs plans Deep understanding of interaction of policies and business, issue spotting and anticipation using data and analytics Critical thinking, predictive and enterprise mindset and outcome-focused performance management Desirable Requirements Master's degree (e.g. MSc) / University Diploma or equivalent in relevant discipline. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Seeking a Global Program Clinical Head (GPCH) for Gene Therapies and Rare Disease early development projects. The GPCH works to ensure early development plans and proof of concept studies are aligned with the Development strategy and leads licensing evaluations for Clinical Development for Gene therapies across various indications. As an integrative leader, the GPCH is accountable to support decision milestones, regulatory requirements and market access for those early compounds in collaboration with relevant other functions. -Leads the strategic planning, execution, and delivery of all global clinical trials across all programs within the assigned TA. Complete oversight of budget and resource allocation within the therapeutic area – including enterprise review of resources across the TAs. Drives operational excellence through process improvement and knowledge sharing across the function. Develops an empowered organization which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Interface from pre-PE through to TDP on standard and RDC priority Gene Therapy and Rare Disease projects and contribute to development of TA strategies including biomarker if appropriateServe (or his deputy) as the Clinical Development Representative on BR clinical/project teams to drive an end to end clinical strategy from First in Human (FIH) to pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) TDP/FDP.Support Business Development & Licensing (BD&L) activities and is member of BD&L Search and evaluation team Leads execution on broad strategic direction and is responsible for delivering the portfolio and project priorities -Complete oversight of budget and resource allocation within the assigned area. Manages resources cross units and/or global projects which may involve managing large teams across multiple sites worldwide -Author/reviewer for relevant SOPs/ departmental procedures -Build best talent and an empowered culture to foster high performance -Drives operational excellence through process improvement and knowledge sharing in the assigned areas and/or across functions -May deputize for/represent functional head This is a generic description. Specific position profiles may vary by Division/Department/unique Position requirements -May deputize for/represent functional head This is a generic description. Specific position profiles may vary by Division/Department/unique Position requirements -Distribution of marketing samples (where applicable) This is a generic description. Specific position profiles may vary by Division/Department/unique Position requirements Minimum Requirements: MD or MD/PhD in Neurology, Neuromuscular or Neurodevelopmental Disorders, Genetics, Pediatrics or Neuroscience background is strongly preferred Advanced clinical training/knowledge in medical/scientific area aligned with TA required. Medical Board certification preferred for MD or equivalent; Clinical practice experience ≥ 10 years (including residency) preferred for MD or equivalent ≥6 years (MD or equivalent)/ ≥ 10 years (PhD or PharmD) of involvement in clinical research or drug development in an industry environment spanning clinical activities in Phases I through III/IV, including submission dossiers Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data This hybrid role can be based in Basel, London, Barcelona, Madrid or Dublin. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a dedicated team united by a drive to deliver significant value to Novartis. You will plan, execute and deliver high quality audits that meet Novartis Internal Audit (IA) methodology standards, strategies and directives. To lead audit teams in activities including assessment of business/information technology risks and evaluation of related internal controls. About the Role Key Responsibilities: Conduct Audits : Lead and perform detailed audits of pharmaceutical supply chain processes, including procurement, manufacturing, distribution, and inventory management. Establish and maintain strong relationship with Novartis internal stakeholders, in particular build strong collaboration to work effectively and seamlessly across our businesses. Risk Assessment : Identify, assess and review potential risks within the supply chain and associated mitigation strategies. Regulatory Compliance : a working knowledge of relevant manufacturing operations regulations, including FDA, EMA, and other global pharmaceutical standards. Process Improvement : Evaluate current processes and recommend improvements to enhance efficiency, reduce costs, and maintain high-quality standards. Reporting : Prepare comprehensive audit reports, summarizing findings, recommendations, and corrective actions for senior management and stakeholders. Data Analysis : As part of the audit or advisory, utilize advanced data analytics and AI where appropriate to identify trends, anomalies, and areas for improvement within the supply chain. Collaboration : Work closely with cross-functional teams, including procurement, logistics, quality assurance, and regulatory affairs, in the understanding and execution of audits and advisories. What you'll bring to the role: Essential Criteria: Degree in a technical or scientific area that contains manufacturing and/or supply chain management, logistics and/or planning. Work experience in technical operations manufacturing and/or supply chain management, planning, logistics and inventory management. Knowledge of pharmaceutical regulations and standards including GMP, GDP and other guidelines. Experience and ability to act in a complex and rapidly changing business environment. Knowledge of process management and/or business process optimization. Fluent in spoken and written English. Willingness to travel (up to 15%) Desirable Criteria: Additional Certifications: Additional relevant certifications such as Certified Supply Chain Professional (CSCP) or Certified in Production and Inventory Management (CPIM), relevant risk management ISO standards, including continuity management experience. Experience with SAP environments. Global Experience: Experience with end-to-end global pharmaceutical supply chains and familiarity with international regulations. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As part of the Drug Product Development Scientific Office you will provide strategic and scientific guidance on integrating new Biologics drug product-related technologies (such as new delivery technologies, new formulation approaches, and new development approaches, e.g. modeling approaches) into CMC projects in collaboration with key stakeholders. You will also support CMC teams in compiling dossiers, drive engagement with industry consortia and health authorities to enable new technologies implementation. In addition, you will propose and lead elaborating scientific solutions to development challenges. About the Role Provide strategic and scientific guidance on integrating new Biologics drug product-related technologies (such as new delivery technologies, new formulation approaches, and new development approaches, e.g., modeling approaches) into CMC projects in collaboration with key stakeholders. Promote a comprehensive approach to drug product development that focuses on the needs of patients and payers while integrating new technologies (pharmaceutical / in-silico) in line with Health Authorities expectations. Engage in industry consortia to shape regulatory environment and influence Health Authorities. Liaise with key stakeholders, including Biomedical Research, Global Program Teams, Devices and Primary Packaging, Regulatory CMC, Quality, and Commercial Manufacturing sites, to encourage them to integrate new technologies into our Biologics product while ensuring their needs for a patient-centric product are met. Support / drive interactions with health authorities through participation on briefing packages Proactively identify, lead/propose solution-oriented plans to resolve scientific drug product development challenges/barriers. Lead innovation programs as needed Minimum requirements 10+ years experience in the biopharmaceutical industry Experience in Biologics development, and specifically DP process development, understanding of drug product manufacturing process operations such as mixing, sterile filtration, and aseptic fill/finish. Experience in DP manufacturing of sterile dosage forms including frozen, liquid, and lyophilized formulations in vials and pre-filled syringes and other presentations Experience in writing regulatory modules including INDs and BLAs Relevant experience of developing and implementing strategies of patient-centered science related work Deep understanding of regulatory guidance from the FDA and EMA for development of biologic drug products, knowledge of USP and Ph. Eur. as it relates to biologics development Learning agility towards new delivery, DP process and other innovative technologies Experience of cross-functional collaboration and leading within a matrix organisation Outstanding influencing skills, leading without authority, excellent presentation and communication skills towards different internal and external stakeholders (senior management, health authorities), outstanding ability to deal with ambiguity, combined with demonstrating strong business acumen Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: This role can be based in Basel Switzerland or the US. If you are based in the US, please apply to REQ #10044653. Regular travel (25-30%) to Hyderabad, India required. LI-#hybrid The Novartis Strategy & Growth team is seeking a new Head of Enterprise Competitive Intelligence to lead the unit responsible for gathering, assessing, and organizing competitive intelligence (CI) that is timely, relevant, and of high-quality. This information supports our pipeline, portfolio, and overall company strategy. The unit focuses on secondary intelligence aligned with company priorities and requests from various units, including strategy, research, development, commercial, communications, and the Executive Committee of Novartis (ECN). The centralized group, consisting of highly skilled associates, will develop a repository for all competitive intelligence and insights across Novartis, making it accessible as needed. About the Role Key Responsibilities: Build and lead a unit to gather intelligence and maintain a central and accessible high-quality data repository across competitive intelligence efforts to facilitate information sharing and reduce duplication Structure the new centralized Enterprise Competitive Intelligence team to gather, assess, organize, and make accessible competitive intelligence aligned with core business priorities Ensure competitive intelligence is timely, relevant, and high-quality to facilitate insights development by strategy, research, development, commercial, communications and other relevant internal teams Gather intelligence via secondary research, AI, and attend global conferences (primary research) Plan, implement and manage an IT infrastructure of all gathered intelligence and developed insights, ensuring it is accessible, consistent, high-quality, and searchable Function as a "librarian" for the broader CI community to facilitate timely access to relevant and high-quality intelligence, including social media listening and sentiment tracking Maintain visibility across internal and external CI databases and all vendors engaged within the CI space Ensure key customers of competitive intelligence are well served, trust the data quality, and see intelligence as a foundation for developing key insights Support other customers of competitive intelligence such as Communications, Investor Relations, and the ECN/CEO office as requested Bring in external best practices and disruptive ideas to strengthen the practice of competitive intelligence Plan, allocate, and manage the Enterprise Competitive Intelligence budget to meet requirements and achieve fiscal responsibility Lead, coach, attract, develop, and retain a high-performing team; develop and implement a people strategy (e.g. manage career progression) Essential Requirements: Education (minimum/desirable): Advanced degree required. Either MD, PhD in relevant discipline or MBA Language: Excellent oral and written English communication skills. Additional languages are a plus Experience/ Professional requirement: ≥10 years of pharmaceutical/biotech organization experience, including working in a globally matrixed environment Past experience in pharmaceutical CI leadership, role in creation of such organization required Energy, drive, achievement oriented, high work ethic Deep understanding of biopharma landscape: companies, assets and early technologies Strong financial and business acumen Strong strategic vision, superior leadership, excellent communication, consensus building, well-developed influencing and negotiation skills Strong written & verbal communication skills coupled with excellent problem-solving, negotiation and conflict resolution skills Collaborative, objective / data driven, senior thought partner Experienced people leader; comfortable leading & managing direct and indirect reports in multiple geographies Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary -Leads the strategic and operational planning and management of the assigned clinical program(s) from an end-to-end clinical operations perspective. The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Your responsibilities will include, but are not limited to: • Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program • Leading development of clinical sections of trial and program level regulatory documents • Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable • Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues • Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas • As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • May work with Biomedical Research/Translational Medical Sciences to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. What you bring to the role: • MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred • Minimum of 7 years of experience in clinical research or drug development • Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. • Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports • Demonstrated ability to establish effective scientific partnerships with key stakeholders • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Previous global people management experience is preferred, though this may include management in a matrix environment. *Final job title and associated responsibilities will be commensurate with the successful candidates’ level of expertise (Senior/Director/Associate) Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary More than 100,000 people across 140 countries are working for Novartis to discover, develop, and successfully market innovative products to prevent and cure diseases, ease suffering, and enhance the quality of life. The Biomedical Research Submission Management, Associate Director will lead the BR cross-functional submission sub-teams to project manage regulatory submissions ensuring that applications and dossiers are prepared in a timely manner and in compliance with Regulatory Authority regulations, guidance, Novartis SOPs and working practices and quality standards. They will also train and guide authors and contributors on regulatory submission requirements and have managerial responsibility for local submission manager team. About the Role Major accountabilities: Managerial responsibility for local submission management team. Manage the preparation of the BR submission components regulatory submission dossiers such as NDA, MAA (i.e., high complexity submissions). Leads submission planning discussions, developing, and maintaining a comprehensive strategic submission plan including a detailed list of dossier content, interdependence, key activities, target governance board review time frames, content delivery timelines, credible dispatch dates and executing this plan. Provides various data visuals, to facilitate awareness of key milestones, closely monitors critical path activities, and ensures transparency of submission status to stakeholders. Provide strategic input relating to submission requirements for migration of submission related supportive documentation for in licensed/joint ventures and acquired assets. Managing the preparation of the subsequent dossier preparation therein. May act as deputy for Head BR Submission Management upon request. Leads continuous improvement activities related to submission processes and regulatory document management within BR. Contribute to the development of key performance indications for the submission management group. Maintain the group’s knowledge of evolving submission requirements, ensuring BR is building strategies to proactively prepare the organization for the future. Participation in audits and inspections and execution of any resultant corrective action plans. May oversee maintenance of specialized expertise on current templates, processes, systems, electronic submission standards regulatory guidelines and legal requirements, as relevant to SM, and training of associates, submission management teams and vendors thereon. Minimum Requirements: Undergraduate degree, preferably in a scientific discipline or life science background or equivalent work experience 5-10 years’ experience working in a regulated, life science environment (pharmaceutical, biotechnology), with 2-3 years’ experience as people manager. Project management experience in the pharmaceutical industry or in a regulatory environment. Expert knowledge of Regulatory Affairs responsibilities from pre-IND through Phases I-IV preferred. Demonstrated leadership and negotiation skills with ability to persuade and influence others (regardless of level) in achieving team and submission objectives. Ability to interpret regulations and gain consensus on a way forward in an environment where there may be more than one way of achieving a successful outcome. Effectively lead multidisciplinary team meetings and drive discussions regarding submission content, timelines, resource allocation, risk management, etc. Ability to proactively identify and mitigate risks and potential bottlenecks, apply sound judgement when determining if/when to escalate issues, and effectively interact with stake holders to ensure transparency of submission progress/status. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Our Immunology Disease Area in Biomedical Research division in Novartis is dedicated to world-class research and finding breakthroughs in treatments for millions of patients worldwide suffering from Immunological conditions and diseases. We are currently seeking a senior level Molecular Pathologist with either a Medical or Veterinary doctoral background and a Pathology certification, to join our teams and lead a lab in the Immunology Disease area and help us tackle some of the most challenging unmet needs. About the Role Job Description You will be part of a cross-disciplinary team, working with various labs in Immunology. A strong emphasis for this role is placed in effective teamwork, networking across teams, and development of successful partnerships with academic leaders worldwide. Your responsibilities will include but not be restricted to: • Lead an experimental pathology lab within the Molecular Pathology group, in Immunology Translational Research. • Use tissue samples from healthy humans, patients suffering from immunological diseases and corresponding animal models for: - Disease understanding - Target validation - Biomarker discovery (pathway-based and pharmacodynamic) • Implement spatial omics technologies • Use of state-of-the-art imaging modalities and digital image analysis to address key scientific questions • Provide pathology expertise for tissue biomarkers in clinical studies • Work closely with multidisciplinary project teams in discovery and translational research. Minimum requirements - What you will bring to the role: • MD or DVM with relevant human or veterinary pathology experience; plus PhD-level research background • You must be a Board-certified Pathologist or Veterinary Pathologist • strong Experimental Pathology background/expertise • Experience in animal mechanistic and disease models as well as human biosamples • Strong background and hands-on expertise in immunohistochemistry and in-situ hybridization, including method development • Strong leadership skills - experienced team leader with direct reports, including professional development of team members • Excellent presentation and communication skills in English (oral and written), innovative thinking and project management skills Desirable: Prior experience in spatial omics will be an advantage Knowledge of or interest in autoimmune and dermatological diseases is highly desirable *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Hybrid #LI-Hybrid About the role: As the Global Program Head, Neuroscience, you will have critical impact of delivering innovation, which drives Novartis’ mission to embark on a journey to reimagine medicine. In this role, you will lead programs through the end-to-end development cycle to seek successful registration and market access. This includes all medical and scientific aspects of clinical trials, programs and studies from the design phase, through implementation and finalization to include scientific and medical input into the final review and sign-off of all pertinent clinical trial. About the Role Your Key Responsibilities: Establish program strategy and execute implementation through milestones and decision points by leveraging cross-functional teams. Drives and implements short- and long-term project vision and strategy, while ensuring alignment across global functions, regions and CPOs in regard to strategy and direction. Communicate clear strategy to program team and functions and ensures that is reflected in the operation. Key contributor to development leadership team and influences direction of area of responsibility with long term approach. May be responsible for strategy at the disease area level encompassing multiple indications, spanning multiple products. Lead multidisciplinary team of functional experts focused on securing global regulatory approval, market access and optimized commercial value of the program, while ensuring quality, compliance (internal and external), within budget, and in a competitive and timely manner, utilizing both internal and external resources necessary. Leverage knowledge, experience, understanding of external stakeholders, internal team capabilities and portfolio needs to develop a compelling and innovative vision and strategy for the program. Deploys and prioritizes resources across development units. Ensures rigorous adherence to quality and compliance. Reports technical complaints, adverse events, special case scenarios related to products within established timelines and protocols. Drives talent acquisition among team members and within their sub-teams, including active selection and de-selection and performance management of the core membership of the program team. Expected travel: approximately 20% US domestic and/or international travel. Role Requirements: Essential Requirements: PhD degree in the related discipline with 10+years of drug development experience, including experience in Global Program Teams and with dossier submission for new or supplemental indication. Deep drug development experience in neuroscience or related disease area. Prior exposure to and strong awareness of regulatory / market access / commercialization requirements particularly for US Clinical background relevant to the programs in the development franchise (medical training or experience in program teams). Experience in product registration and major health authority interactions. Longstanding experience of leading multidisciplinary teams. Innovative strategic attitude. Desirable Requirements: M.D. highly desirable. Clinical and or research experience in neurology/neuroscience, preferably neurodegeneration Strong external network in field of neuroscience. Strong publication record with expertise recognized in the field of neurodegeneration or other compelling credentials relevant to neuroscience drug development. Experience in using AI/digital in research and or development. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: this role can be based in Basel Switzerland, Cambridge MA, or East Hanover, NJ US. If applying in the US, please apply to REQ-10039396. The Strategy & Growth team is seeking a new Therapeutic Area Strategy Head leader for Neuroscience. The Therapeutic Area Strategy Head will lead a therapeutic area focused team in the creation and ongo-ing update of a holistic and aligned Enterprise portfolio strategy for their TA. The candidate will work closely with the Global Innovative Medicines TA teams as well as across BioMedical Research (BR), and Development. The candidate will bring a passion for innovation, deep industry experience, scientific ac-umen and strong judgement to guide internal choices and drive sustainable growth in the short, mid and long-term for their respective TA. This individual will have both a broad and deep understanding of their core Therapeutic Area (TA) to derive insightful and differentiating competitive advantages over our peers by bringing a third-party view around key strategic levers and external analyses, trends, and white space opportunities. Additionally, they will conduct targeted primary research. About the Role Key responsibilities: Provides external perspective and identifies opportunities: Builds and maintains in-depth knowledge of the TA (early pipeline to commercial); including disease models; responsible for ongoing assessment of peer companies with heavy exposure in the TA. Educates, updates and provides external views to all internal stakeholders. Provides insight within key portfolio governance processes (diligence and external landscape mapping with BD&L and M&A) Supports identification of growth accretive opportunities, indications, disease spaces and rejection of low value Supports Group Investor Relations and the CEO Office with dissemination of key strategic insights Ongoing collection and synthesis of scientific and commercial insights for the TA Owns therapeutic area portfolio strategy and prioritization: Leads the process of creating, maintaining and updating Enterprise-wide TA portfolio strategy; including DA and molecule selection to drive mid- and long-term growth in collaboration with IM, GDD, & NIBR Identifies potential pipeline gaps, makes recommendations to address Works closely with key stakeholders (e.g., PS&A GPSC, IM-US, MAP team, NIBR, GDD) to facilitate portfolio decision making, prioritization and trade-offs Internal and External Commercial and Pipeline Modelling: Oversees assessments of programs fit to current portfolio strategy and facilitates central review for assets inside and outside current priorities (e.g., at Innovation Management Board (IMB) Provides consolidated commercial and development inputs to support business cases for internal and external assets and programs Provides outside-in independent view of internal assumptions around core pipeline Leads the development of assessment of external opportunities (e.g., forecast assumptions) Others: Coaches, attracts, develops, and retains top talents; partners with P&O leadership to develop people strategy (e.g. organization development, performance, career development). Plans, allocates, and manages TA strategy financial budget by anticipating expenditures, accurately forecasting resource needs/costs and properly accounting for expenses to meet requirements and achieve fiscal responsibility. Minimum Requirements: Advanced degree or equivalent experience in life science/healthcare required; MBA highly desirable Significant (3+ years) and recent (post 2017) local US experience preferred; local US experience includes working within the US market (with the local US customers, US health care systems / systems of care, US payors / accounts, etc.), driving US market strategy Excellent oral and written English communication skills. Additional languages are advantageous ≥10 years of pharmaceutical/biotech experience from either banking, consulting or biopharma covering drug development and ideally commercialization with an ability to work in a matrix environment Ability to comfortably engage with the C-suite and mid-career associates to influence and challenge with excellent interpersonal and leadership skills Strong financial and business acumen with strong understanding of biopharma landscape; companies, assets and early technologies Strong strategic vision, superior leadership, excellent communication, consensus building, and well-developed influencing and negotiation skills Excellent conflict resolution skills to facilitate agreement and buy-in at the senior-most levels Experience leading and managing a team with a variety of insights from science to commercial and proven coaching and mentoring experience Cross-functional experience preferred (in particular access experience) Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary When we put our heads together, we can do brilliant work. And when we do brilliant work, we can achieve remarkable things for patients as we positively transform healthcare. We are looking for an Early Portfolio Global Program Head (GPH). The Global Program Head is a key player in the strategic leadership of Novartis, inspiring action through transformative vision and robust strategies for our programs. They drive the entire program lifecycle, having sole accountability and responsibility to deliver enterprise value by defining the program’s strategic vision, optimizing life cycle management, and driving the integrated development plans to ensure successful regulatory and access outcomes. As an integrative leader, the GPH represents the program internally and externally, embodies its values, maintains program commitments, and safely navigates the complex, ever changing healthcare landscape to deliver innovative medicines that improve and extend patients’ lives. Their role includes managing the Global Program Team, fostering career growth and equally emphasizing performance accountability within a high-performance and collaborative environment. The GPH holds a crucial and pivotal role in managing stakeholder relationships using exceptional communication skills, effectively influencing and involving stakeholders in decision-making processes, and anticipating and flexibly adjusting strategies to meet stakeholder expectations and responses. This role can be based in Basel Switzerland or East Hanover, US. About the Role Major Accountabilities Strategic Leadership Drive the program's transformational vision, devise an adaptable strategy that anticipates future trends and challenges, and translate strategies into practical, impactful plans. Seek out and combine complex internal/external elements to inform business decision-making, identify key issues in complex scenarios, and ensure clarity. Embody an enterprise leader that works across the entire Novartis research-development-commercial continuum to understand the impact of decisions, the benefit of diverse perspective, and the power of our shared purpose. Deliver organization-wide impact through an understanding and respect for an evolving technological landscape, including knowing when and how to incorporate new tools into existing strategies while evolving ahead of anticipated capabilities (e.g., precision medicine, AI, blockchain, nanotechnology). End-to-End Program Lifecycle Accountability The GPH has sole accountability of and responsibility to deliver enterprise value by defining the asset’s strategic vision, optimize life cycle management, and drive the integrated development plans to ensure successful regulatory and access outcomes. Leads the design of the Target Product Profile (TPP) and the Integrated Development Plan (IDP). Accountable for end-to-end program leadership, including formally representing the program internally and externally, instigating innovation in early-stage development processes, issuing recommendations, making decisions to ensure the program success and asset value optimization, and ultimately propelling the program through preliminary testing and approval stages. Uphold regulatory compliance and meet initial stage commitments regarding prototype quality, timeline, projected cost, and potential value. Candidly communicate program impact projections and assess the early-stage commercial viability. Together with the Line Functions, Managing and Developing the Global Program Team Empower the team through clear roles/responsibilities, prioritizing individual growth, and holding team accountable for ambitious goals. Nurture a well-performing team that fosters collaboration and supportive challenge. Stakeholder Management Maintain positive relationships with stakeholders, ensuring clear, concise communication throughout the program lifecycle, and handle conflicts diplomatically. Build positive relationships with stakeholders; provide clear, concise communication about preliminary venture details and expertly navigate any arising conflicts. Enhance stakeholder understanding of program objectives/risks, influence their expectations through scientific and evidence-based communication, and involving stakeholders in decision-making processes. Adjust strategies based on stakeholders' needs, expectations, and potential responses. Foster stakeholders' understanding of project aims and inherent risks during initial development, shape their expectations through scientific evidence-based dialogue, and include them in decision-making processes. Adapt strategies by anticipating stakeholders concerns, needs, and possible responses. Education Minimum requirements Doctoral degree or equivalent, MD preferred Min 8 years of drug development experience, including experience in dossier submission for new or supplemental indication Exposure to full drug development lifecycle Managing cross-functional teams and intense cross-functional collaboration and alignment Leading teams through influence without direct authority Communicating clearly and concisely with various audiences, adjusting messaging, style, tone, and details to best fit different audiences Experience in forming and driving transformative visions and strategic plans for early-stage programs. Background in team management, developing roles, and fostering a high-performance culture. Previous interactions with early stage/scientific stakeholders, emphasizing clear communication and involvement in decision-making. Experience in anticipating and crafting adaptive, resilient strategies for early-stage innovation and scenario planning. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Als Automatiker übernehmen Sie die Wartung und Instandhaltung gemäss Instandhaltungs-Plan und sind für Störungsbehebung und verhindern von Anlagenstillständen zuständig. About the Role Ihre Verantwortungsbereich: • Wartung und Instandhaltung gemäss Instandhaltungs-Plan. Sie sind in erster Linie zuständig für die technische Verfügbarkeit aller Anlagen bzw. Nebenaggregate inklusive der vorbeugenden Instandhaltung (TPM). Diese Tätigkeiten beinhalten spezielle GMP-Anforderungen und sind gemäss den gültigen Richtlinien durchzuführen • Störungsbehebung und verhindern von Anlagenstillständen. Frühzeitiges Erkennen von Problemen und Einleitung der ersten Schritte zur Behebung • Technische Bereitstellung der Anlagen gemäss Produktionsauftrag und Unterstützung von Projektarbeiten und Engineering Gruppe • Kennt die Prozessabläufe in seinem Arbeitsbereich im Detail • Pflege von Dokumentationen. Ordnungsgemässe Durchführung von Schichtübergaben und einwandfreie Dokumentation sämtlicher Aktivitäten (Logbücher, SAP). Konsequente Verfolgung der Einhaltung von GxP, Daten-Integrität, GSU-Richtlinien und SOP’s Was Sie zur Rolle mitbringen: • Abgeschlossene Berufsausbildung zum Automatiker (oder vergleichbar) • Erfahrungen in Mess- und Regeltechnik, Siemens (S7 und TIA), Scada-Systeme, Bildverarbeitung mit Kamerasystemen, PC-Kenntnisse (Hard- und Software) • Pneumatische und hydraulische Grundkenntnisse • GMP- und GSU-Kenntnisse sowie Erfahrung im Arbeiten nach SOP’s • Deutsch (fliessend), Englisch (Grundkenntnisse) • Von Vorteil sind Berufserfahrung in der Pharma-, Kosmetik- oder Nahrungsmittel-Industrie Warum Novartis? Unser Ziel ist es, die Medizin neu zu erfinden, um das Leben der Menschen zu verbessern und zu verlängern. Unsere Vision ist es, das angesehenste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie können wir das erreichen? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns jeden Tag antreiben, unsere Ziele zu erreichen. Werde Teil dieser Mission und schließe dich uns an! Erfahre hier mehr: https://www.novartis.com/about/strategy/people-and-culture Was du erhältst: Alles, was du über unsere Leistungen und Prämien wissen musst, findest du im Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis setzt sich für die Schaffung eines hervorragenden, integrativen Arbeitsumfelds und vielfältiger Teams ein, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Barrierefreiheit und Anpassungen Novartis ist bestrebt, mit allen Personen zusammenzuarbeiten und angemessene Vorkehrungen für sie zu treffen. Wenn du aufgrund einer Erkrankung oder Behinderung eine angemessene Vorkehrung für einen Teil des Einstellungsverfahrens benötigst oder detailliertere Informationen über die wesentlichen Funktionen einer Position erhalten möchtest, sende bitte eine E-Mail an E-Mail schreiben und teile uns die Art deines Anliegens und deine Kontaktinformationen mit. Bitte gib in deiner Nachricht die Nummer der Stellenausschreibung an. Tritt unserem Novartis-Netzwerk bei: Wenn diese Stelle nicht zu deiner Erfahrung oder deinen Karrierezielen passt, du aber auf dem Laufenden bleiben und mehr über Novartis und unsere Karrieremöglichkeiten erfahren möchtest, tritt hier dem Novartis-Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary •Gerätebediener •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten nach Produktionsplan, um die rechtzeitige Produktion des Produkts mit der Qualität und Quantität in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. •Service-Operator •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten gemäß Produktionsplan in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien. Führen Sie routinemäßige operative Support-Aktivitäten nach dem Herstellungsprozess und Zeitplan durch und ermöglichen Sie die zeitnahe Produktion des Produkts mit der Qualität und Quantität •Dokumentationsspezialist Admin Der Dokumentationsspezialist Admin verwaltet die Änderung, Bearbeitung, Verteilung, Überprüfung und Archivierung von GMP-Fertigungsdokumenten und die Ausgabe der Batch-Datensätze, um sie in der Qualität und innerhalb der Fristen an die Produktion zu liefern. Der Dokumentationsspezialist Admin stellt eine Reihe von Verwaltungsaufgaben sicher, die für das ordnungsgemäße Funktionieren des Geräts erforderlich sind. About the Role Major accountabilities: Participation to the manufacturing processes Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines Minimum Requirements: Transportation experience General HSE Knowledge Knowledge of GMP Art Curator Transportation Classification (i.e. IATA or DOT) expertise Manufacturing Process Execution English language You’ll receive: Breakdown of benefits received in this role. Include flexible working, learning and development opportunities as well. WhyNovartis? 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Commitment to Diversity & Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve. Accessibility and accommodation Novartis group is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/en_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards